objective(s): prostaglandins have been shown to mediate the gastro-protective effect of sodium hydrosulfide (nahs) but effect of nahs on mrna expression of prostaglandin e2 receptors (ep1, 3-4; eps) has not been investigated. therefore, this study designed to evaluate the effect of nahs on mrna expression of eps receptors in response to mucosal acidification and distention-induced gastric acid ...

kawasaki disease (kd) is an acute febrile systemic vasculitis of childhood characterized by elevated levels of inflammatory mediators at the acute stage. high-dose intravenous immunoglobulin (ivig) is well accepted as a conventional therapy for kd. the aim of the present study was to determine the expression level of toll like receptors (tlrs) and their corresponding signaling mediators in pbmc...

previous studies have shown that ascorbic acid (aa) plays a crucial role in mammalian brain as avitamin and neuronal modulator. there is increasing evidence indicating that dopaminergic system and aacould affect learning and memory processes. in addition, vitamin c acts as a dopamine antagonist in thebrain. the aim of the present study was to evaluate the intra-hippocampal co-administration of ...

background: it is not yet known which types of toll-like receptors (tlrs) are most effective in helicobacter pylori (h. pylori) recognition. it is also not known which gastric zones have the most prominent roles in tlr-mediated bacterial recognition. the aim of this work was to analyze the expression of tlr2 and tlr4 in biopsy specimens from h. pylori-infected patients. methods: thirty-eight pa...

conclusions regarding the findings of this study, it can be concluded that erα possibly cannot play an important role in the tumorigenesis and prognosis of the investigated malignant salivary gland tumors. results for acc, only one specimen expressed the er, and this was assessed as moderate. no specimens of mec expressed the er. the comparison of er expression between the two groups was not me...

Adenosine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Receptors [112]) are activated endogenous ligand adenosine (potentially inosine also at A3 receptors). Crystal structures for antagonist-bound [155, 316, 224, 62], agonist-bound [379, 205, 206] and G protein-bound A2A [49] have been described. The of an A1 receptor [130] adenosine-bound receptor-Gi complex [87] resolve...

Receptors. In their Communication (e202216011), Jan J. Weigand et al. report the selective separation of lithium, magnesium, and calcium using 4-phosphoryl pyrazolones as pH-regulated receptors.

Adenosine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Receptors [110]) are activated endogenous ligand adenosine (potentially inosine also at A3 receptors). Crystal structures for antagonist-bound [153, 313, 221, 61], agonist-bound [375, 203, 204] and G protein-bound A2A [49] have been described. The of an A1 receptor [128] adenosine-bound receptor-Gi complex [86] resolve...

Previous research indicates that high blood urea nitrogen (BUN) concentrations are associated with decreased fertility in lactating dairy cows.This experiment was done to evaluate the effects of equine chorionic gonadotropin (eCG) administration (with or without eCG) on fertility of lactating dairy cows with different levels of BUN subjected to fixed-time artificial insemination (FTAI).Ovulatio...

Receptors. In their Communication (e202216011), Jan J. Weigand et al. report the selective separation of lithium, magnesium, and calcium using 4-phosphoryl pyrazolones as pH-regulated receptors.