conclusions pericardial effusion was a rare finding in this case of langerhans cell histiocytosis. pericardial effusion in langerhans cell histiocytosis, which is an unusual presentation, should be considered when the patient experiences respiratory distress. introduction langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs. langerhans cell histiocyt...

A 5-year-old National Show horse mare presented with a soft mass on the left dorsolateral aspect of the tongue. Over the next 2 years, the mare developed numerous, similar, coalescing masses that extended along the left dorsolateral aspect to the tip of the tongue. Microscopically, the bases for these masses were slender, fusiform, mesenchymal cells that formed compact whorls around myelinated ...

Background: Researchers suggest that benign breast disease (BBD) is a key risk factor for breast cancer. The present study aimed to determinate the risk level of breast cancer in terms of various BBD subgroups.Methods: A meta-analysis was performed to determinate the risk of breast cancer associated with BBD. Observational studies (traditional case-control studies, nested case-control studies, ...

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a benign systemic proliferative disorder of histiocytes resembling the sinus histiocytes of lymph nodes. The typical clinical features of this disease include bilateral painless lymphadenopathy, fever, and polyclonal hyperglobulinaemia. The condition may present with extranodal involvement in 43% of cases, and cutaneous...

The interface blunt-prosthesis is the subject of stress and friction due to forces that act in the walking stage. The dermal wounds that can appear due to this stress and frictions can heal due to normal process of regenerative of dermal layers. In some cases, the normal process of wound healing can fail and some abnormal forms can develop: keloid and hypertrophic scars. These abnormal forms ca...

Pure red cell aplasia (PRCA) is a heterogeneous disorder. Immunologic abnormalities have recently been uncovered suggesting that both cell-mediated and humoral immune mechanisms may be of etiological importance in PRCA. Utilizing a technique for the cloning of bone marrow erythroid precursors, we determined the in vitro proliferative capacity of erythroid cells obtained from 21 patients with PR...

Historic changes in the criteria for pathologic diagnosis and classification of lupus membranous nephropathy (LMN) have precluded definitive descriptions of the natural history, prognosis, and treatment of this disorder. The interim practice, based on the 1982 World Health Organization classification system, of admixing membranous and proliferative lupus nephropathies under the rubric of LMN ha...

Normal sodium levels in the extracellular fluid are range of 135–145 mmol/L. Low serum (hyponatraemia) is a common water and electrolyte balance disorder. Dehydration overhydration most causes hyponatraemia children. This paper describes case 2.5-year-old boy admitted to paediatric ward due pneumonia. The child showed reluctance intake, hypoosmolar with hypouricaemia, increased urinary excretio...

Aim: The opening of mitochondrial permeability transition (mPT) pore is an important event in the execution mitochondrial-mediated apoptosis. Some bioactive compounds elicit their chemotherapeutic effects against tumor/cancer cells via induction Annona muricata, a medicinal plant, folklorically used treatment tumors and cancers. This study therefore aimed at investigating effect methanol stem b...

BACKGROUND Self-healing juvenile cutaneous mucinosis is a rare disease affecting young people characterized by transient cutaneous lesions and sometimes mild inflammatory symptoms. The deep dermal and subcutaneous features of this disorder have not yet been well described. OBJECTIVE The purpose of our study was to present 3 cases of self-healing juvenile cutaneous mucinosis in which the histo...