نتایج جستجو برای: protein isoforms
تعداد نتایج: 1242693 فیلتر نتایج به سال:
While alternative splicing is known to diversify the functional characteristics of some genes, the extent to which protein isoforms globally contribute to functional complexity on a proteomic scale remains unknown. To address this systematically, we cloned full-length open reading frames of alternatively spliced transcripts for a large number of human genes and used protein-protein interaction ...
Abstract Introduction Traumatic brain injury (TBI) is a global public health burden. Although neurogenesis occurs post-injury, achieving long term survival of newly generated neurons remains elusive. High Mobility Group Box protein 1 (HMGB1) pivotal cytokine in hosting the neuro-inflammatory response to injury, but also mediates during physiological development. In this review, we examine curre...
The RNA sequencing data sets available for different fish species show a potentially high variety of forms enzymes just in teleosts. This is primarily considered an effect the first round whole-genome duplication with mutations duplicated genes (isozymes) and alternative splicing mRNA (isoforms). However, abundance transcript variants not necessarily reflected active proteins. We have investiga...
BACKGROUND Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While involved in the development and functioning of many different cell types, recent studies point to important roles for TCF4 in the nervous system. Specifically, human TCF4 gene is implicated in susceptibility to schizophre...
background hepatocellular carcinoma (hcc), a major fatal cancer worldwide, is induced by different etiological factors in the liver. objectives to gain insight into serum protein profiling of hcc with different etiologies. patients and methods we subjected the sera of hbv-hcc, hcv-hcc, non-b non-c-hcc patients, and healthy volunteers to two-dimensional gel electrophoresis (2-de) and liquid chro...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید