a key factor in spermatogenesis and disorders associated with this protein have been recognized to be related to male infertility. although it was suggested that this protein could have different functions during germ cell development, no studies have been conducted to uncover the mechanism of this potential function yet. here, we analyzed the expression pattern of rbmy protein isoforms in test...

background: withania somnifera l. dunal, (ashwagandha) belongs to the family solanaceae and is known as ‘indian ginseng’ in the traditional system of medicine. objectives: in the present investigation, comparative analysis was carried out between two different ecotypes of w. somnifera related to total soluble protein and antioxidant enzyme activity [catalase (cat), superoxide dismutase (sod) an...

withania somnifera (l.) dunal is an erect evergreen shrub commonly known as ashwagandha. it is widely used in ayurvedic, and in the traditional pharmacopeia system of india. it is one of the major ingredients in many formulations prescribed for a variety of musculo-skeletal conditions including arthritis and rheumatism. in the present study, variations in the quality and quantity of proteins an...

Abstract This study was conducted to evaluate the role of oxidative stress in roots of eight wheat genotypes with different drought tolerance, subjected to drought stress. For analyzing the changes of antioxidant enzymes, native PAGE analyses of protein extract were performed. The roots of wheat seedlings showed one unambiguous isoform of superoxide dismutase (SOD) and catalase (CAT). Eight iso...

Background: Promyelocytic leukemia protein (PML) is a tumor suppressor protein that is involved in myeloid cell differentiation in response to retinoic acid (RA). In addition, RA acts as a natural morphogen in neural development. Objectives: This study aimed to examine PML gene expression in different stages of in vitro neural differentiation of NT2 cells, and to investigate the possible role o...

Background Asthenozoospermia accounts for almost 50% of the cases of male infertility. Our study investigating phosphoproteins differentially expressed in asthenozoosperm has identified the phosphoproteins relevant to sperm motility and the signature molecules likely to be altered in asthenozoospermia. The 66 phosphoproteins differentially expressed included four alpha tubulin isoforms which we...

Transforming growth factor betas (TGF?s) are one of the most widespread and versatile cytokines. The three mammalian TGF? isoforms, ?1, ?2, and ?3, and their receptors regulate proliferation of neuronal precursors as well as survival and differentiation in neurons of developing and adult nervous system. Functions of TGF?s has a wide spectrum ranging from regulating cell proliferation and differ...

Human d-aspartate oxidase (hDASPO) is a FAD-dependent enzyme responsible for the degradation of (d-Asp). In mammalian central nervous system, d-Asp behaves as classical neurotransmitter, it thought to be involved in neural development, brain morphology and behavior, appears several pathological states, such schizophrenia Alzheimer's disease. Apparently, human DDO gene produces alternative trans...

Prostate-specific antigen (PSA) was purified to homogeneity from human seminal plasma by ion-exchange chromatography on a CM-Sephadex C-50 and by gel filtration on a Sephacryl S-200 column. A single 33-kDa protein band appeared in SDS-PAGE. High pressure liquid chromatography (HPLC) of the purified protein produced a single peak, while isoelectric focusing demonstrated the presence of five diff...