The Cyclic Voltammetric (CV) behavior of Alizarin Red-S (ARS), which is an Anthraquinone dye was examined by utilizing TX-100 modified carbon nanotube paste electrode (TX-100MCNTPE). The surfactant utilized is TX-100, and it has been found that it has good electrocatalytic activity towards ARS. Distinctive parameters like pH, scan rate, detection limit have been studied in the potential range o...

Measurement of 17-hydroxyprogesterone (17-OHP) in daily dried blood spot profiles via radioimmunoassay is a convenient and accepted method for monitoring of glucocorticoid therapy in Congenital Adrenal Hyperplasia. Characteristics of this method that serve to limit its clinical usefulness include its lack of specificity for 17-OHP, and a relatively high limit of detection. Mass Spectroscopy is ...

Ochratoxin A is a nephrotoxic and renal carcinogenic mycotoxin and is a common contaminant of various food commodities. Eighty six kinds of foodstuffs (1032 food samples) were collected in 2011-2013. High-performance liquid chromatography with fluorescence detection was used for ochratoxin A determination. Limit of quantification of the method varied between 0.01-0.2 μg/kg depending on the food...

introduction: the limited resolution of the imaging system causes partial volume effects (pves). these results in spreading of image counts to the neighboring pixels. this phenomenon is called spill-out effect. this study aimed at quantifying pves using imagej. methods:technetium-99m solution of concentration of 74 kbq/ml was filled into spheres a, b and c of diameters: 26 mm, 20 mm and 16 mm r...

Nucleic acid amplification can provide sensitive and specific molecular detection and quantification. Since its introduction PCR has been the dominant amplification technology; its widespread use has stimulated improvements in enzymes, instrumentation, and analytical methods. Initial use of PCR was largely qualitative: positive target detection, or inference of target absence above a detection ...

A simple, sensitive isocratic method for the detection and quantification of ciprofloxacin in plasma and urine has been developed. The assay consisted of reversed-phase HPLC with ultraviolet detection. Plasma proteins were removed by a fast and efficient procedure. For the urine samples, the only required sample preparation was dilution. Separation was achieved on a C18 reversed-phase column. T...

A method for the quantification of low levels of amorphous content of maltitol with hyper-DSC (high speed DSC) was developed. The method is based on the fact that the change of specific heat ( Cp) at the glass transition is linearly proportional to the amorphous content. Twelve synthetic mixtures with various degrees of crystalline and amorphous maltitol were prepared. Cp was determined at both...

Cardiovascular diseases such as acute myocardial infarction and heart failure accounted for the death of 17.5 million people (31% of all global deaths) in 2015. Monitoring the level of circulating N-terminal proBNP (NT-proBNP) is crucial for the detection of people at risk of heart failure. In this article, we describe a novel ultra-sensitive NT-proBNP test (us-NT-proBNP) that allows the quanti...

The current research aimed to quantify melittin (MEL) in Iranian honey bee (Apis mellifera meda) venom. To this end, a liquid chromatography-electrospray ionization-ion trap tandem mass spectrometry (LC-ESI-IT-MS/MS) approach was employed. Melittin is the main toxic peptide of honey bee venom with various biological and pharmacological activities. It was extracted with...