The pellagragenic effect of leucine (Leu) has been proposed to involve modulation of L-tryptophan (Trp) metabolism along the hepatic kynurenine pathway. Here, we discuss some of the mechanisms suggested and report the effects in healthy volunteers of single doses of Leu (4.05-6.75 g) administered in a 16-amino acid mixture on concentrations of plasma Trp and its kynurenine metabolites. Flux of ...

We consider the problems posed by the increasing heterogeneity of network services and applications, in particular the convergence of data, voice and televisual networks and applications. A possible approach by which this heterogeneity can be tamed and taken advantage is to embrace diversity at the levels above IP. Just as routers interconnect arbitrary media, the net can be made of gateways th...

The confusion matrix of the 62 characters task (Fig. 1) shows that most of the errors are due to confusions between digits and letters and between lower-and upper-case letters. Figure 1. Confusion matrix of the NIST SD 19 MCDNN trained on the 62-class task: correct labels on vertical axis; detected labels on horizontal axis. Square areas are proportional to error numbers, shown as relative perc...

the main purpose of this paper is to apply of islamic transactions rules on iran capital market contracts by studying the economic actions of the individuals in tehran stock market. based on the theories of four major islamic laws, i.e., no damage rule, gaining from invalid activities rule, peril rule and usury rule; the basic islamic assumptions is drawn in order to testify in the capital mark...

This paper describes an interactive neural network model that predicts the quality of cast ceramic products using multiple quantitative and qualitative inputs. This has been done to enable a major sanitary ware manufacturer to reduce product waste by better control of the slip casting process. The input variables describe the raw materials, ambient conditions and line settings for the ceramic c...

“pacta sunt servanda” is one of the most fundamental principles in the common law and iranian legal systems, which have been exposed to exceptions in the process of time. these exceptions are part of general doctrine of frustration. iranians exceptions to this rule are named as “ta`azzor” and “ta`assor” rules. doctrine of frustration in common law includes three subdivision theories: “impossibi...

one of the subjects about the “la zarar” rule that always had been controversial is survey for positive aspect of it. not only opponents but also researchers that sought to answer the objections of the positive aspect of the rule enter the discussion on the assumption that the evidence of the “la zarar, rule is the la zarar hadith, in story of ansari man and samorah-ibn jondab discored. this as...

The Parkland formula is the standard for calculating the initial intravenous fluid rate for resuscutation after thermal injury. However, it is cumbersome when used by those with modest burn training. We propose an easier method to calculate fluid requirements that can be initiated by first-line providers. Burn size is estimated by using the Burn Size Score (BSS), which is then crossreferenced w...