Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The pat...

Salivary gland tumors present diverse histopathological aspects and show various biological behavior. At present, the immunohistological method using anti-BrdU monoclonal antibodies, which was originated in the field neurosurgery, has been tried extensively in various fields of medicine. Using this method, the authors have attempted to detect biological characteristics of salivary gland tumor t...

Salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  Minor  salivary  gland  tumors (MSGTs) are uncommon and make up about 10% of all salivary gland neoplasms. The clinical and histopathological distribution of these tumors vary geographically. A case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. The tumor invaded into the anterior ...

introduction:  the use of radioactive iodine (131i) has become an important adjunct to the treatment of thyroid cancer and hyperthyroidism. salivary gland has the ability to concentrate radioactive iodine under normal circumstances. salivary gland dysfunction and dry mouth are the common side effectsof high-dose radioiodine therapy. the purposeof this study was to determine the absorbed dose of...

introduction: malignant salivary gland tumors are rare entities. despite advances in surgery, radiation therapy and chemotherapy, the rate of the mortality and five-year survival has not been improved markedly over the last few decades. the activation of egfr- ras-raf signaling pathway contributes to the initiation and progression of many human cancers, promising a key pathway for therapeutic m...

a case of pleomorphic adenoma in sweat gland is reported here. the histopathologic report confirmed the diagnosis. pleomorphic adenoma is most common in salivary glands but very rare in sweat glands. pleomorphic adenoma in sweat gland and the similar tumors of eccring sweat gland are described that bear a striking resemblance to pleomorphic adenomas of salivary gland. upon closer examination, t...

neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. submandibular gland tumors are relatively rare and...

Background: Salivary gland tumors are among malignancies that have high recurrence rate. Immune responses in salivary gland tumors have not been well elucidated. T helper type 1 (Th1) and Th2 cytokines have been reported to play a role in the outcome of head and neck cancers. Objective: To evaluate the serum levels of interferon gamma (IFN- γ), as the hallmark of Th1 cytokines, and interleukin-...

Salivary gland neoplasms account for 0.5-2% of all tumors worldwide, and can display a remarkable range of morphological diversity between different tumor types. The aim of this retrospective study was to present the clinico-pathologic characteristics of salivary gland neoplasms in a tertiary referral hospital in northwest region of Nigeria. Clinical and histopathological records of patients wi...