We present a computational modeling and numerical simulation framework that enables the integration of multiple physics and spatiotemporal scales in models of physiological systems. This framework is the foundation of the IUPS (International Union of Physiological Sciences) Physiome Project. One novel aspect is the use of CellML, an annotated mathematical representation language, to specify mod...

The Gaussian kernel has long been used in the classical multiscale analysis. The purpose of the paper is to propose the uniform B-spline as an alternative for the visual modeling. A general framework for various scale-space representations is formulated using theB-spline approach. In particular, the evolution of the wavelet models can be well understood from such an approach. Most of the wavele...

Methods Practice-based research was used to collect client data (N=321) before and after a massage provided by one of 24 licensed massage therapists in Iowa. The pre-massage survey included items regarding their chief complaint, the client expectations of massage scale, the numeric rating scale for pain, and the Positive and Negative Affect Schedule Expanded form (PANAS-X). The post-massage sur...