Schistosomiasis affects millions of people in developing countries and is responsible for more than 200,000 deaths annually. Because of toxicity and limited spectrum of activity of alternatives, there is effectively only one drug, praziquantel, available for its treatment. Recent data suggest that drug resistance could soon be a problem. There is therefore the need to identify new drug targets ...

background: obesity  was a dangerous chronic disease. physicians recommended drug therapy just in a few of obese patients in spite of many health risks. weight control can be improved comorbidities of obesity like hyperlipedemia, hyperinsulinoma, acanthosis nigricans and hypertension. materials and methods: this article reviewed the available original and review literatures which had been publi...

drug abuse is prevalent in all countries across the world and  induces variety of adverse effects (1). health problems arising from drug abuse commonly cause significant health challenges in the affected population and deteriorate many aspects of the patients’ performance and quality of life. comorbidities are discovered in 60 to 75% of addict patients, suffering from various drug-related disor...

due to high resolution power of sulfated cyclodextrins (hs-cds), utilization of these selectors for chiral resolution of 7 basic and 2 zwitterionic drugs have been examined. experiments were performed on a hp3dce instrument equipped with an on-column diode array uv absorbance detector. fused silica capillaries with an inner diameter of 50 ?m, an outer diameter of 365 ?m, and a total length of 4...

conclusions anti-tuberculosis drugs-induced hepatotoxicity caused treatment interruption in 5.5% of the patients with tuberculosis. the majority of the patients with dih were above fifty, and 50% the cases occurred during the first two weeks after treatment onset. physicians must carefully and closely monitor such patients. background hepatotoxicity is one of the most frequent adverse events th...

extract   until recent years pharmacological researches focused on pathogeneses and abnormality in organogenesis but now researchers are studying drugs physiological disorders in pregnancy. these studies are specially focused on mothers and fetus, regulatory mechanism of passing drugs through placenta and movement of drug' materials between barriers of milk and blood in the breast. also th...

introduction: since prescription is a way of communication between the pharmacist, physician and patient, inattention to its principles may result in mis-consumption or incomplete use of the medicine, drug interactions, and increased probable adverse effects. therefore, this research tried to investigate physicians' commitment to principles of prescription writing for outpatients insured by med...