OBJECTIVES To develop prognostic models for risk of a breakthrough seizure, risk of seizure recurrence after a breakthrough seizure, and likelihood of achieving 12-month remission following a breakthrough seizure. A breakthrough seizure is one that occurs following at least 12 months remission whilst on treatment. METHODS We analysed data from the SANAD study. This long-term randomised trial ...

OBJECTIVE To evaluate seizure outcome following epilepsy surgery for patients with temporal lobe epilepsy and evaluate is gender and race/ethnicity influence it. METHODS Data were obtained from the discharge database of the University of Alabama at Birmingham, Epilepsy Center, between 1985 and 2001. The sample consisted of all patients with a primary diagnosis of medically intractable tempora...

OBJECTIVES Febrile seizures recur frequently. Factors increasing the risk of febrile seizure recurrence include young age at onset, family history of febrile seizures, previous recurrent febrile seizures, time lapse since previous seizure <6 months, relative low temperature at the initial seizure, multiple type initial seizure, and frequent febrile illnesses. Prevention of seizure recurrences s...

Objective: This study was conducted with the objective to identify aetiology of first seizure in adults and evaluate their clinical profile, treatment practices recurrence. Methods: A prospective observational at Neuro-sciences department a tertiary care hospital cum medical research institute Northern India from April-2017 October-2018. total 114 adult patients aged 18 years or above, who pres...

UNLABELLED Convulsions triggered by fever are the most common type of seizures in childhood, and 20% to 30% of them have recurrence. The prophylactic treatment is still controversial, so we performed a systematic review to find out the effectiveness of continuous phenobarbital and intermittent diazepam compared to placebo for febrile seizure recurrence. METHOD Only randomized, double-blind, p...

OBJECTIVE To provide evidence-based recommendations for treatment of adults with an unprovoked first seizure. METHODS We defined relevant questions and systematically reviewed published studies according to the American Academy of Neurology's classification of evidence criteria; we based recommendations on evidence level. RESULTS AND RECOMMENDATIONS Adults with an unprovoked first seizure s...