Previous studies have led to a model in which the promoter-specific recognition of prokaryotic transcription initiation factor, sigma (σ), is core dependent. Most σ functions were studied on the basis of this tenet. Here, we provide in vitro evidence demonstrating that the intact Bacillus subtilis primary sigma, σ(A), by itself, is able to interact specifically with promoter deoxyribonucleic ac...

given a graph $g$, let $g^sigma$ be an oriented graph of $g$ with the orientation $sigma$ and skew-adjacency matrix $s(g^sigma)$. then the spectrum of $s(g^sigma)$ consisting of all the eigenvalues of $s(g^sigma)$ is called the skew-spectrum of $g^sigma$, denoted by $sp(g^sigma)$. the skew energy of the oriented graph $g^sigma$, denoted by $mathcal{e}_s(g^sigma)$, is defined as the sum of the n...

It has been demonstrated that about 10% of the Escherichia coli genes are under direct or indirect control of RpoS. Therefore, Weber et al. [2005] proposed that this sigma subunit should be considered a second vegetative sigma factor under non-optimal growth conditions. In this report we demonstrate that in the phosphoenolpyruvate:carbohydrate phosphotransferase system-deficient (PTS(-)) deriva...

Let $R$ be a ring, $sigma$ be an endomorphism of $R$ and $M_R$ be a $sigma$-rigid module. A module $M_R$ is called quasi-Baer if the right annihilator of a principal submodule of $R$ is generated by an idempotent. It is shown that an $R$-module $M_R$ is a quasi-Baer module if and only if $M[[x]]$ is a quasi-Baer module over the skew power series ring $R[[x,sigma]]$.

The sigma-2 receptors are promising therapeutic targets because of their significant upregulation in tumor cells compared with normal tissue. Here, we characterize CM572 [3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)-6-isothiocyanatobenzo[d]oxazol-2(3H)-one] (sigma-1 Ki ≥ 10 µM, sigma-2 Ki = 14.6 ± 6.9 nM), a novel isothiocyanate derivative of the putative sigma-2 antagonist, SN79 [6-acetyl-3-(...

Background and Aims: Six sigma is the latest version of total quality management. It is quantitative goal for process performance. With increasing demands for improved accuracy and reliability of the results, Six Sigma is gaining increased visibility in the clinical laboratory process outcomes. The aim of study was to evaluate the quality of analytical phase performance in a clinical biochemist...