Objective Unrecognized left main coronary artery disease (LMCD) is often fatal; however, accuracy of non-invasive tests for diagnosing LMCD is still unsatisfactory. This study was performed to elucidate single-photon emission computed tomography (SPECT) detection of LMCD using quantitative coronary angiography (QCA) data. Materials and Methods Fifty-five patients (39 men; mean age, 68.1 ± 10....

Objective(s): Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with ahigh frequency. However, there is no data on the correlation of cognitive...

This article presents and validates a newly developed GATE model of the Siemens Inveon trimodal imaging platform. Fully incorporating the positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomography (CT) data acquisition subsystems, this model enables feasibility studies of new imaging applications, the development of reconstruction and correct...

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Objective(s): The latest single-photon emission computed tomography (SPECT)/computed tomography (CT) reconstruction system, referred to as xSPECT Bone™, is a context-specific reconstruction system utilizing tissue segmentation information from CT data, which is called a zone map. The aim of this study was to evaluate theeffects of zone-map enhancement incorporated into the ordered-subset conjug...

eart diseases are one of the leading cause of death in developed countries, for this reason an early diagnosis of the diseases is absolutely necessary. In order to do so, several tools are used, such as, electrocardiogram (EKG), chest X-Ray (Computed Tomography, CT), blood and stress tests, echocardiogram (ECG), cardiac magnetic resonance (MRI) and nuclear medicine (Single Photon Emission Compu...

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Because scintigraphic images lack anatomical information, single photon emission tomography (SPECT) and positron emission tomography systems (PET) are combined physically with CTs to compensate for this drawback. In our work, we present a method where the CT is replaced by a 3D ultrasound device. Because in this case a mechanical linkage is not possible, we use an additional optical tracking sy...

Introduction: Photon attenuation in tissues is the primary physical degrading factor limiting both visual qualitative interpretation and quantitative analysis capabilities of reconstructed Single Photon Emission Computed Tomography (SPECT) images. The aim of present study was to investigate the effect of attenuation correction on the detection of activation foci following statistical analysis w...