scleroderma is a multisystem autoimmune connective tissue disease, cliaracterized by hardening of the skin. hv had 25 patients in the iranian pediatric unit of rheumatology over 10 years. there was female predominance if.m = 4/1, 80% female, 20% male). the age of onest was from 6 months to 16 years, the mean age being 10 years. the symptoms and signs were: nonpitting edema in 16%, liard skin in...

Introduction:Neurofibromatosis is a genetic disease characterized by multifocal benign tumors of peripheral nerves, called neurofibromas, and pigmented spots on the skin which inherited as autosomal-dominant. The most common form of the disease is neurofibromatosis type 1, also known as von Recklinghausen's disease of the skin. When an individual has small number of lesions in a limited region ...

Objective: As a rare autoimmune disease, pemphigus vulgaris has a poor prognosis especially in lack of proper medical support. This blistering disease involves both the skin and mucus membranes. The challenge is improving the healing process of skin lesions of which, superimposed infections are among the main causes of the disease mortality. Accordingly, we aimed to assess the treatment options...

we encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. this child was being fed with a low-protein diet when the skin disorder developed. a deficiency in plasma levels isoleucine, was confirmed. supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. we assume that in our patient the sk...

albright syndrome is a rare condition, usually appears in the early years of life and characterized by bending or thickening of long bones. in girls, of endocrine glands disorders especially precocious puberty are the most common symptoms. also, brown pigments in the skin are another sing of this syndrome. certain mucosal and skin pigments are considerable features of the disease. etiology and ...

superficial fungal infections are one of the most prevalent skin diseases worldwide.according to clinical reports, dermatophytosis has been the most prevalent form ofsuperficial infections. it is well documented that the epidemiology of skin infectionsmight change over time. the aim of this study was to evaluate the epidemiology andprevalence of superficial fungal infections in dormitory studen...