DESCRIPTION TRELSTAR  DEPOT contains a pamoate salt of triptorelin, and triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH or GnRH) with greater potency than the naturally occurring LHRH. The chemical name of triptorelin pamoate is 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-serylL-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycine amide (pam...

Entacapone is an inhibitor of catechol O methyltransferase (COMT), used in the treatment of Parkinson’s Disease as an adjunct to levodopa and carbidopa therapy. It is a nitrocatechol structured compound with a relative molecular mass of 305.29. The chemical name of entacapone is (E) 2 cyano 3 (3,4 dihydroxy 5 nitrophenyl) N,N diethyl 2 propenamide. Its empirical formula is C H N O and its struc...

We introduce a method for calculating the extent to which chain non-crossing is important in the most efficient, optimal trajectories or pathways for a protein to fold. This involves recording all unphysical crossing events of a ghost chain, and calculating the minimal uncrossing cost that would have been required to avoid such events. A depth-first tree search algorithm is applied to find mini...

We present a method for decomposing modal formulas for processes with the internal action τ . To decide whether a process algebra term satisfies a modal formula, one can check whether its subterms satisfy formulas that are obtained by decomposing the original formula. The decomposition uses the structural operational semantics that underlies the process algebra. We use this decomposition method...

DESCRIPTION Aloxi (palonosetron hydrochloride) is an antiemetic and antinauseant agent. It is a selective serotonin subtype 3 (5-HT3) receptor antagonist with a strong binding affinity for this receptor. Chemically, palonosetron hydrochloride is: (3aS)-2-[(S)-1-Azabicyclo [2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1oxo-1Hbenz[de]isoquinoline hydrochloride. The empirical formula is C19H24N2O.HCl, w...

We present a method for decomposing modal formulas for processes with the internal action τ . To decide whether a process algebra term satisfies a modal formula, one can check whether its subterms satisfy formulas that are obtained by decomposing the original formula. The decomposition uses the structural operational semantics that underlies the process algebra. We use this decomposition method...

DESCRIPTION TEVETEN HCT 600/12.5 mg and TEVETEN HCT 600/25 mg (eprosartan mesylate­ hydrochlorothiazide) combine an angiotensin II receptor (AT1 subtype) antagonist and a diuretic, hydrochlorothiazide. TEVETEN (eprosartan mesylate) is a non-biphenyl non-tetrazole angiotensin II receptor (AT1) antagonist. A selective non-peptide molecule, TEVETEN is chemically described as the monomethanesulfona...

This paper presents a method for the decomposition of HML formulas. It can be used to decide whether a process algebra term satisfies a HML formula, by checking whether subterms satisfy certain formulas, obtained by decomposing the original formula. The method uses the structural operational semantics of the process algebra. The main contribution of this paper is the extension of an earlier dec...

Background: Literature reports suggest that phytochemicals, such as isoflavones found in soybeans, impair reproductive function in animals and raise the possibility that consuming soy infant formula could alter hormonally sensitive organ development in children. Objective: This study compared reproductive organs volumes and structural characteristics in children at age 5 y who were enrolled in ...

Allostery represents a fundamental mechanism of biological regulation that is mediated via long-range communication between distant protein sites. Although little is known about the underlying dynamical process, recent time-resolved infrared spectroscopy experiments on a photoswitchable PDZ domain (PDZ2S) have indicated that the allosteric transition occurs on multiple timescales. Here, using e...