There are increasing concerns that exposure to unmetabolized folic acid, which results from folic acid intakes that overwhelm the liver's metabolic capacity, may be associated with adverse effects. In this paper, we examined the folic acid status of women of reproductive age in relation to dietary intake and the effect of folic acid supplementation (1.1 mg or 5 mg). Plasma unmetabolized folic a...

fabrication and electrochemical characterization of a sensor for the determination of epinephrine (ep), uric acid (ua) and folic acid (fa) is described. the sensor  was prepared using carbon paste electrode (cpe) modified with 3,4-dihydroxybenzaldehyde-2,4-dinitrophenylhydrazone (ddp) and carbon nanotubes (cnts), which makes the modified electrode highly sensitive for the electrochemical detect...

We established the cutoff value for plasma folic acid, using plasma homocyst(e)ine as the functional marker. To do this, we investigated the relationship of the plasma folic acid of 103 apparently healthy adults with their fasting plasma homocyst(e)ine and with their plasma homocyst(e)ine 6 h after oral methionine challenge (100 mg/kg). We also studied the relationship of their plasma folic aci...

OBJECTIVE Many health professional groups recommend folic acid supplementation for all women able to become pregnant. In this study, we document folic acid supplement use among a sample of women receiving routine gynecologic care. METHODS A short questionnaire was administered to 322 women aged 18-45 years who were seeking routine gynecologic care at participating clinics in Little Rock, Arka...

Mandatory folic acid fortification of wheat flour for making bread was implemented in Australia in September 2009, to improve the dietary folate status of women of child-bearing age, and help reduce the incidence of neural tube defects in the population. This paper presents estimates of folic acid intake in the target population and other subgroups of the Australian population following impleme...

objective(s) the present study aimed to investigate the effects of a fat soluble antioxidant, coenzyme q10 (coq10) and folic acid on learning and memory in the rats with intracerebroventricular injection of streptozotocin (icv-stz), an animal model of sporadic type of alzheimer's disease. materials and methods the lesion groups were injected bilaterally with icv-stz (1.5 mg/kg b.wt., in no...