QUESTION Some of my pregnant patients have been prescribed various potencies of topical corticosteroids. Do these carry the same fetal risks as systemic corticosteroids? ANSWER Pregnant women can be reassured that there is no apparent increased risk of adverse fetal effects when using topical corticosteroids during pregnancy, although some data do suggest fetal growth restriction with more po...

Guidelines on systemic corticosteroids in chronic obstructive pulmonary disease (COPD) exacerbation rely on studies that excluded patients requiring ventilatory support. Recent publication of studies including ICU patients allows estimation of the level of evidence overall and in patients admitted to the ICU. We included RCTs evaluating the efficacy and safety of systemic corticosteroids in COP...

Giant cell arteritis (GCA) is an ophthalmic emergency which requires early diagnosis and treatment with high dose systemic corticosteroids in order to prevent permanent visual loss. However, systemic corticosteroids have significant ocular side effects including cataract formation, raised intraocular pressure, and less commonly, central serous chorioretinopathy (CSCR). We report a case of visua...

CHEST, VOL. 63, NO. 4, APRIL 1973 SUPPLEMENT sone; 2 ) systemic corticosteroid administration restores the responsiveness of adenyl cyclase to betaadrenergic stimulation; 3 ) systemic corticosteroids inhibit the increased ATPase activity, possibly with a concomitaiit decrease in transport, contractile and secretory processes; and 4 ) corticosteroids at high levels may inhibit cyclic A vIP phosp...

Inhaled corticosteroids (IC) are commonly used for the treatment of respiratory diseases. Although these medications are generally considered safer when compared to oral systemic corticosteroids, there is evidence for potential systemic and local adverse effects with their use. Therefore, dentists should be aware of these adverse effects, especially the commonest local effects that can involve ...

While the majority of anterior uveitis presentations are idiopathic and respond well to topical corticosteroids, in a minority cases there underlying systemic inflammatory processes that com...