Purpose A pinhole collimator is routinely used to increase the resolution of scintigraphy. This prospective study was conducted to determine the interest of Tc-MIBI pinhole SPECT for the preoperative localization of parathyroid lesions in primary hyperparathyroidism. Methods All patients underwent a neck US, TcO4 and Tc-MIBI planar images, and two consecutive SPECT with a parallel (C-SPECT) and...

BACKGROUND Ultrasound (US) and technetium-99m sestamibi scintigraphy (MIBI) are used to determine the localization of abnormal glands in cases of primary hyperparathyroidism (PHPT). Intraoperative intact parathyroid hormone (iPTH) monitoring is a reliable examination used to cure PHPT. The aim was to assess the necessity of intraoperative iPTH monitoring. METHODS Sixty patients were examined ...

A 39-year-old woman presented to our clinic with incidentally detected hyperglycemia. Her medical history revealed no specific illness except for a previously diagnosed 2 cm sized thyroid nodule which was diagnosed benign nodular hyperplasia by ultrasound (US) guided fine-needle aspiration (FNA) biopsy for 3 years ago. Laboratory findings show hyperglycemia, hypercalcemia, hypophosphatemia, and...

Objective(s): In this study, we aimed to analyze the relationship between the diagnostic ability of fused single photon emission computed tomography/computed tomography (SPECT/CT) images in localization of parathyroid lesions and the size of adenomas or hyperplastic glands. Methods: Five patients with primary hyperparathyroidism (PHPT) and 4 patients with secondary hyperparathyroidism (SHPT) we...

Introduction: We aimed to investigate of effect of left bundle branch block (LBBB) on perfusion and functional parameters in dipyridamole Tc99m-MIBI gated myocardial perfusion SPECT which may be helpful in interpretation of myocardial perfusion imaging. Methods: We studied 70 patients with low pre-test probability of coronary artery disease in two groups:  35 patients with LBBB and  35 subject...

Abstract Introduction The success of minimally invasive parathyroid surgery is largely based on accurate preoperative localization adenomas. In the U.K, NICE guidance recommends either ultrasound scanning alone or combined with sestamibi scintigraphy to help guide surgery. recent past, surgeon performed (SUS) has been adopted in North America and Australia for a sensitivity 63–91%. This was equ...

Primary hyperparathyroidism (PHP) affects 0.5%-1% of the adult population and presents with classical signs of renal lithiasis, cholecystolithiasis, gastrointestinal ulcerations, depression, and osteoporosis. Parathyroid adenoma, hyperplasia and rarely carcinoma are the underlying pathology. Synchronous thyroid and parathyroid pathologies are described in multiple endocrine neoplasia. We report...

We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ultrasonography and computed tomography of the neck with contrast enhancement revealed a soft tissue...

A 17-year-old boy with hyperparathyroidism exhibited a large cyst in the left hemi-thorax on his chest X-ray. The cyst was identified as a hydatid cyst. He was referred for biphasic methoxy isobutyl isonitrile (MIBI) parathyroid scan. A discrete ectopic parathyroid was detected in the left upper mediastinum in addition to accumulation of the MIBI tracer in the cyst wall. Using radio-guided occu...