Telomeres are located at chromosome ends and their length (TL) has been associated with aging and human diseases such as cancer. Whole blood DNA is frequently used for TL measurements but the influence of preanalytical conditions and DNA isolation methods on TL quantification has not been thoroughly investigated. To evaluate potential preanalytical as well as methodological bias on TL, anonymiz...

background: abnormal patellar height is associated with anterior knee pain and several conditions that affect the patellofemoral joint. the aim of this study was to 1) report the incidence of patella alta and patella baja and 2) investigate whether the normal limits of the insall-salvati ratio is applicable in adult middle-easterners. methods: a radiographic review of the lateral radiographs of...

As research related to healthspan and lifespan has become a hot topic, the necessity for reliable practical biomarker of aging (BoA), which can provide information about mortality morbidity risk, along with remaining life expectancy, increased. The chromosome terminus non-coding protective structure that prevents genomic instability is called telomere. continual shortening telomeres, affects th...

Relationships between fish length and otolith length, width mass were investigated in the two nearly threatened silurid species (Siluriformes) Ailia coila (Hamilton, 1822) Ompok pabda Hamilton, collected from Ganga River at Narora, India. The relationships (OL) total (TL), (OWd) TL, weight (OWe) TL are expressed by linear regression models; for A. coila, OL = 0.0291 + 0.8541, OWd 0.0306 0.2241,...

Telomeres, the nucleotide repeats and protein complex at chromosome ends, are required for chromosomal stability and are important markers of aging. Patients with dyskeratosis congenita (DC), an inherited bone marrow failure syndrome (IBMFS), have mutations in telomere biology genes, and very short telomeres. There are limited data on intra-individual telomere length (TL) variability in DC and ...

thymus is a medicinal plant which contains one of the world's top ten essential oils, exhibiting antibacterial, antioxidative, food preservative and mammalian age-delaying properties. this work was aimed at identifying between-species variations requiring for selecting appropriate parents for hybridization. six iranian endemic thymus accessions belonging to thymus daënensis, t. eriocalyx and t....

Coney (Cephalopholis fulva) sampled from recreational and commercial vessels along the southeastern coast of the United States in 1998-2013 (n = 353) were aged by counting opaque bands on sectioned sagittal otoliths. Analysis of otolith edge type (opaque or translucent) revealed that annuli formed in January-June with a peak in April. Coney were aged up to 19 years, and the largest fish measure...