background: although giant cell tumor (gct) is considered to be a primary benign bone tumor, its aggressive behavior makes its diagnosis and treatment, difficult and challenging. this is especially true in distal radius where gct appears to be more aggressive and difficult to control locally. we report our clinical outcome of en-block resection and reconstruction with non-vascularized fibular a...

we report occurrence of a rare case of giant cell tumor (gct), in a 28-year old woman, arising from anterior arc of right 6 th rib during pregnancy. it progressed rapidly during breast-feeding period, mimicking malignant bone tumor at delayed presentation.

Adult onset asthma and periocular xanthogranuloma (AAPOX) is a rare non-Langerhans histiocytosis characterized histopathologically by a periocular infiltration of foamy histiocytes and Touton giant cells. Benign hyperplasia with plasma cell infiltration is classically described in eyelids or lymph nodes of AAPOX patients. It is also a characteristic feature of IgG4-related disease (IgG4-RD), a ...

two rare cases of extra-articular diffuse variant giant cell tumor of the tendon sheath are presented, at the elbow of a 68-year-old female and the foot of a 56-year-old male. both patients presented with a palpable masses and marginal excision was performed; histological sections confirmed the diagnosis of extra-articular giant cell tumor. no adjuvant therapy was administered. at the last foll...

this case report describes a 59-year-old woman with a giant basal cell carcinoma on the face neglected for 11 years. surgical resection of the lesion resulted in a 13 × 11 cm defect. issues regarding the adequately safe surgical margins and the management of the resultant defect through modern wound dressing technologies are discussed. keywords : giant basal cell carcinoma, modern dressing, gel...

ependymomas accounts for about 2%–6% of cns and 60%–70% of spinal cord tumors. several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. in spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. this report presents a case of giant cell ependymoma...

Abstract Background Erdheim-Chester disease (ECD) is a rare multisystemic histiocytic disorder of unknown etiology. Isolated neck involvement has not been reported in literature. Case presentation An elderly male presented to our outpatient department with swelling 1-month duration. Contrast-enhanced CT scan the showed mass involving left thyroid/perithyroidal tissue encirclement common carotid...

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

abstract: objective: giant cell tumor of soft parts is a rare neoplasm that mainly affects adulst and the elderly and is usually located in the extremities. here we report a child with giant cell tumor of soft tissue, which is a very rare condition in childhood. clinical presentation: a 5 year old girl presented with a 5 month history of left lower extremity pain. she had developed paraplegia b...