Prostate-specific antigen (PSA) is the one of the most valuable tumor markers for the early detection and management of prostate carcinoma, but not an ideal one because of poor specificity in the case of prostatic hypertrophy and other benign conditions. In order to overcome this drawback some other parameters as is free to total ratio (F/T) PSA and PSA density (PSAD) are introduced. It has bee...

PURPOSE To establish the prognostic value of total and free prostate secretory protein of 94 amino acids (PSP94) and the PSP94-binding protein (PSPBP) following radical prostatectomy. EXPERIMENTAL DESIGN One hundred and eighty-five serum samples were obtained from patients with localized prostate cancer prior to treatment with radical prostatectomy at Virginia Urology (Richmond, VA). Patients...

BACKGROUND The effect of alcohol consumption on prostate health and reproductive hormone profiles has long been investigated and currently, no consensus has been reached. Additionally, large studies focusing on this topic are relatively rare in China. PURPOSE To investigate the association of alcohol consumption with prostate measurements and reproductive hormone profiles in Chinese populatio...

Pride is an emotion that may influence a competitive athlete’s sports performance and mastery. The purpose of this study was to develop scale measure the pride traits in (Trait Scale for Athletes: TPSA) examine characteristics. University student-athletes (N = 463) completed TPSA, focusing on subjective emotional episodes other scales important personality constructs including self-esteem, resi...

BACKGROUND We evaluated the association of total and free forms of serum human kallikrein 2 (hK2) and prostate-specific antigen (PSA) with prostate cancers of unfavorable prognosis. METHODS We retrospectively measured total PSA (tPSA), free PSA (fPSA), and total hK2 (thK2) in preoperative serum samples from 867 men [and assessed free hK2 (fhK2) measured in 577 of these men] treated with radic...

BACKGROUND The utility of conventional prostate-specific antigen (PSA) measurements in blood for monitoring rapid responses to treatment for prostate cancer is limited because of its slow elimination rate. Prior studies have shown that free PSA (fPSA), intact PSA (iPSA) and human kallikrein-related peptidase 2 (hK2) are eliminated more rapidly after radical prostatectomy. In contrast, all three...

BACKGROUND Prostate cancer (PCa) is the most common male cancer in Europe and the US. The early diagnosis relies on prostate specific antigen (PSA) serum test, even if it showed clear limits. Among the new tests currently under study, one of the most promising is the prostate cancer gene 3 (PCA3), a non-coding mRNA whose level increases up to 100 times in PCa tissues when compared to normal tis...

BACKGROUND To characterise the association between demographic and clinical factors and levels of total prostate specific antigen (tPSA) and its molecular derivatives complexed PSA (cPSA), free PSA (fPSA) and the ratio of free to total PSA (%fPSA)] in New Zealand Maori, Pacific Islanders and Europeans, in order to determine whether reported ethnic differences in PSA can be explained by lifestyl...

Endobronchial metastasis from prostate cancer is a rare neoplasm which metastasizes to the proximal central or subsegmental bronchus, in a bronchoscopically visible range. We present a 72-year-old man with a left superior lobar bronchus mass, intrapulmonary metastases, and bone metastases, mimicking primary lung bronchogenic carcinoma. Increasing tPSA, decreasing fPSA/tPSA level, and prostatic ...