نتایج جستجو برای: trimethylsilylation

تعداد نتایج: 65  

A mild, efficient and fast method for the trimethylsilyl (TMS), tetrahydropyranyl (THP) and methoxymethyl (MOM) protection of alcohols and phenols in the presence of sulfonated rice husk ash (RHA-SO3H) is reported. All reactions were performed at room temperature in high to excellent yields. All the products are separated and compared with authentic samples and/ or identified using different ty...

Journal: :Mass spectrometry reviews 1996
I Matsumoto T Kuhara

In most developed countries, neonatal mass screening programs for the early diagnosis of inborn errors of metabolism (IEM) have been implemented and have been found to be effective for the prevention or significant reduction of clinical symptoms such as mental retardation. These programs rely primarily on simple bacterial inhibition assays (the "Guthrie tests"). We developed a new method for sc...

2005
PETER D. KLEIN

The absorption and metabolism of dietary nucleic acids have received less attention than those of other organic nutrients, largely because of methodological difficulties. We supplemented the rations of poultry and mice with the edible alga Spirulina platensis, which had been uniformly labeled with '3C by hydroponic culture in 13CO2. The rations were ingested by a hen for 4 wk and by four mice f...

2013
Chendong Yang Crystal Harrison Eunsook S. Jin David T. Chuang A. Dean Sherry Craig R. Malloy Matthew E. Merritt Ralph J. DeBerardinis

Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of C and analysis of extracted metabolites) or a dynamic view of a few reactions (hyperpolarized C spectroscopy). Moreover, while hyperpolariza...

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