Type 2 diabetes mellitus (T2DM) is one of the most important epidemic diseases in the world this century, and accounts for 90% of cases of diabetes globally. Brazil is one of the most important examples of the alarming picture of T2DM in emergent societies, being the country with the fourth largest number of people with diabetes. The aim of this paper is to review the literature on diabetes in ...

considering that mapk (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (t2dm), we have recently investigated the reported genetic polymorphism from genome wide association study in map3k1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of mapk signal...

The aim of this observational study was to describe the profile of subjects with type 2 diabetes mellitus from Gujarat, India. The study was performed with newly-diagnosed 622 type 2 diabetic subjects who attended the Department of Diabetology, All India Institute of Diabetes and Research and Yash Diabetes Specialties Centre (Swasthya), Ahmedabad, during August 2006-January 2009. The subjects c...

AIMS SGLT2 inhibitors are a new class of oral hypoglycemic agents used in type 2 diabetes (T2DM). Their effectiveness in maturity onset diabetes of the young (MODY) is unknown. We aimed to assess the response to a single dose of 10 mg dapagliflozin in patients with Hepatocyte Nuclear Factor 1 Alpha (HNF1A)-MODY, Glucokinase (GCK)-MODY, and type 2 diabetes. METHODS We examined 14 HNF1A-MODY, 1...

We aim to determine the frequency of preeclampsia (PE) spectrum disorders among subjects with diabetes by subtype: Type 1 mellitus (T1DM); 2 DM (T2DM); gestational diet controlled (A1GDM); medication GDM (A2GDM); and hyperglycemia in early pregnancy. hypothesized a higher rate PE severe features those T1DM T2DM.

Background The goal of diabetes control should be feasible in order to minimize the risk of its adverse events and to reduce its burden and cost on patients. The current study aimed to assess the status of glycemic control in male and female patients with Type 2 Diabetes Mellitus (T2DM) in Kerman, Iran.   Methods In the present study, 500 T2DM (300 women and 200 men) from the Kerman Coronary Ar...

BACKGROUND Type 2 diabetes mellitus (T2DM) has a strong genetic component, and its prevalence is notably increased in the family members of T2DM patients. However, there are few studies about the family history of T2DM. We carried out this study to assess the influences of family history on clinical characteristics in T2DM patients. METHODS This is a cross-sectional study involving 651 T2DM p...

Type 2 Diabetes Mellitus (T2DM) is a group of metabolic syndromes characterized by hyperglycemia associated with the defect insulin action. Globally, number people diabetes mellitus (DM) has been increased four folds in past three decades because urbanization and lifestyle change [1].

Introduction Hypertension is common and integral to the pathophysiology of type 2 diabetes (T2DM). It affects the majority of patients, and is an important modifiable risk factor for both microand macrovascular disease. The recent publication of the South African Hypertension Society guideline (SAHS) 2011 and the SEMDSA guideline for the management of type 2 diabetes affords us the opportunity ...

Type 2 diabetes mellitus (T2DM) became the most prevalent health problem. Almost half of world's people are ignorant that have diabetes. Menopause occurs as an important alteration in women through which take place change sex hormones, distribution fat،s body, and metabolism, altogether participate metabolism disease such type mellitus. Several studies appeared association between TCF7L2 gene d...