T he field of neurotrophin biology has made great advances in recent years to include a greater understanding of signaling pathways and broader understanding of the diverse biological roles of these molecules. This review will focus primarily on the nerve growth factor family of neurotrophins and how recent descriptions of the molecular function of both the ligands and the receptors have helped...

number of new drugs which have appeared during the last three years have been included and the author has been very wise in exercising a judicious caution in their selection. The sulphanilamide group of drugs which, is still in an experimental stage has received adequate attention. The book has been well written and brings out with great clarity the really important actions and therapeutic uses...

In this paper we study the properties of systems of bounded arithmetic capturing small complexity classes and state conditions sufficient for such systems to capture the corresponding complexity class tightly. Our class of systems of bounded arithmetic is the class of secondorder systems with comprehension axiom for a syntactically restricted class of formulas Φ ⊂ Σ 1 based on a logic in the de...

Animal venoms have been used for therapeutic purposes since the dawn of recorded history. Only a small fraction, however, have been tested for pharmaceutical utility. Modern computational methods enable the systematic exploration of novel therapeutic uses for venom compounds. Unfortunately, there is currently no comprehensive resource describing the clinical effects of venoms to support this co...

n-acetyl cysteine (nac), as a nutritional supplement, is a greatly applied antioxidant in vivo and in vitro. nac is a precursor of l-cysteine that results in glutathione elevation biosynthesis. it acts directly as a scavenger of free radicals, especially oxygen radicals. nac is a powerful antioxidant. it is also recommended as a potential treatment option for different disorders resulted from g...

the 21st century nanotechnology has the potential to make a huge impact on sustainability; but to achieve this potential, nanotechnology is all about getting more function on less space. in other hand, nanotechnology is one of the most extremely important components in sustainable development. it has the potential to reduce the environmental impact and energy intensity of structures, as well as...

abstractâ recreation and leisure services, is one of the including factors affecting the quality of tourist experience in tourism destinations, something that also can directly affect them about their staying. the purpose of this study is quantitative and qualitative survey of recreational - leisure uses in the coastal strip of babolsar. methodology of this paper is descriptive- analytical. sou...

Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...