BACKGROUND Candidate genes associated with idiopathic forms of autism overlap with other disorders including fragile X syndrome. Our laboratory has previously shown reduction in fragile X mental retardation protein (FMRP) and increase in metabotropic glutamate receptor 5 (mGluR5) in cerebellar vermis and superior frontal cortex (BA9) of individuals with autism. METHODS In the current study we...

Central positional nystagmus arises due to disruption of brainstem or cerebellar vestibular networks. Most patients with central had lesions focal diffusion pontine lesion. From a clinical perspective, the presence is thus highly predictive in posterior fossa, including apparatus, nuclei, and midline structures within vermis. We experienced infarction dentate nucleus.

Background: Rhombencephalosynapsis is characterized by agenesis/hypogenesis of the cerebellar vermis along with the fusion of the cerebellar hemispheres in the midline. There are less than 50 cases in the literature, and adult cases are extremely rare. In this paper, an adult patient with rhombencephalosynapsis is reported. Case: A 24-year-old female was admitted with the complaint of headache....

Six dogs with cerebellar dysplasia, in which the cerebellar vermis was hypoplastic, are described. Clinical signs in these dogs were noted around 2 weeks of age and included ataxia, dysmetria, and intention tremors. A variable portion of the caudal cerebellar vermis was absent in each dog; portions of the cerebellar hemispheres and flocculus also were absent in some of them. Neurons in certain ...

In a previous communication' evidence was adduced to indicate that the dorsal accessory olives of the medulla are connected with the dorsal part of the vermis (lingula, lobus centralis, culmen and declive) and that the ventromedian accessory olives and the ventral limbs of the inferior olives are connected with the ventral part of the vermis (folium, tuber, pyramis, uvula and nodulus). Holmes a...