BACKGROUND The biological mechanisms in the association between the metabolic syndrome (MS) and various biomarkers, such as 25-hydroxyvitamin D (vit D) and magnesium, are not fully understood. Several of the proposed predictors of MS are also possible predictors of parathyroid hormone (PTH). We aimed to explore whether PTH is a possible mediator between MS and various possible explanatory varia...

       Many studies have proved that the dietary micronutrient has an inhibitory effect against experimentally induced rat hepatocarcinogenesis. The present work is an attempt to understand combined effect of selenium (Se) and vitamin D3 (vit D3) on some potential protein expression markers of carcinogenesis, such as metallothionein (MT), P53 and antioxidant levels during ...

Background and Objective: Tuberculosis (TB) remains an ongoing major public health problem in the world. In recent years, experimental evidenc suggests a link between TB and Vitamin (Vit) D. This study was conducted to determine serum Vit D, calcium (Ca), phosphorus (P), and parathormone (PTH) levels in untreated pulmonary TB (PTB) patients. Materials and Methods: In this case control study, 5...

Methods Upon the approval of local ethical committee, a total of 491 patients admitted to ICU of two centers between January 2014 and January 2015 were evaluated retrospectively. The patients who were under 18 years old, elective surgery and whose serum vitamin D levels and outcomes were unknown were excluded from the study. A total of 213 patients were included in the study and divided into 2 ...

Vitamin D deficiency is associated with cardiovascular and metabolic diseases. Cardiovascular diseases, in turn, are responsible for mortality of patients with type 2 diabetes (T2D). We investigated whether a single parenteral dose of 25(OH) Vit D could improve the endothelial function in T2D patients with ischemic heart disease. A randomized, placebo-controlled, and double-blind trial was perf...

Vitamin D deficiency is associated with cardiovascular and metabolic diseases. Cardiovascular diseases, in turn, are responsible for mortality of patients with type 2 diabetes (T2D). We investigated whether a single parenteral dose of 25(OH) Vit D could improve the endothelial function in T2D patients with ischemic heart disease. A randomized, placebo-controlled, and double-blind trial was perf...

Combination of 1 alpha(OH) D3(vit D) and ethylene glycol induced renal or ureteral stones or both consisting of calcium oxalate in male Wistar rats. This study investigates the effect of EHDP on calcium oxalate stone using the rat model. EHDP reduced the frequency of renal stone and calcium content in the kidney, and reduced the size of the stones in the renal pelvis and ureter. EHDP biochemica...

Background: Vitamin D, especially its most ac ve metabolite 1,25‐dihydroxyvitamin D3(Vit D) is essen al in regula ng a wide variety of biologic processes, such as regula ng mesangial cell ac va on. The objec ve of this study was to assess the histopathological changes of effec veness of Vit D as a protec ve agent against radia on induced lung injury. Materials and Methods: Eighteen Wistar rats ...

Background: Paraquat (PQ) is one of the most important herbicides used in agriculture. Objectives: This study was conducted to compare preventive effect vitamin D (Vit D) and N-acetylcysteine (NAC) against kidney injury rats versus promotive PQ. Methods: In this study, were divided into six groups. The control group (group 1) received normal saline, Vit 2) intraperitoneal (IP) injections of+Vit...