Vitamin D status is usually assessed by measuring the serum concentration of 25-hydroxyvitamin D [25(OH)D]. Its measurement is important as a clinical indicator of nutritional vitamin D deficiency, which is one of the causes of osteoporosis (1). Vitamin D exists in two forms: cholecalciferol (vitamin D 3) and ergocalciferol (vitamin D 2). Vitamin D 2 is further metabolized to 25(OH)D 2. Vitamin...

W e read the article “High prevalence of vitamin D deficiency among newly diagnosed youth-onset diabetes mellitus in north India” written by Daga and cols. with interest (1). We find it is very valuable for the literature, as the study design was a prospective one. The authors showed that vitamin D levels were lower in patients with young-onset diabetes compared with healthy controls. They also...

Background: Due to the interruption of the EHC pathway in NAFLD patients, we hypothesized that parenteral vitamin D supplementation is superior to oral in vitamin D insufficient patients with NAFLD. Therefore, this study aimed to compare the efficacy of oral and parenteral routes of vitamin D supplementation on serum 25(OH) vitamin D levels in patients with NAFLD. Methods: In this prospective ...

background stem cell transplantation has become as a novel treatment  for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. improved survival of transplant recipients has raised awareness of post-transplant complications. one of these complications is transplant-related osteoporosis. methods  in this manuscript we review prevention methods for transplant-related ...

There is substantial evidence that the prevalence of vitamin D deficiency is unacceptably high in the population, and this requires action from a public health perspective. Circulating 25-hydroxyvitamin D [25(OH)D] is a robust and reliable marker of vitamin D status and has been used by numerous agencies in the establishment of vitamin D dietary requirements and for population surveillance of v...

PURPOSE Vitamin D deficiency has been linked to chronic diseases, such as diabetes mellitus, obesity and autoimmune disease. However, data on the vitamin D status and its association with precocious puberty in girls are limited. We aimed to investigate the association between serum 25-hydroxyvitamin D (25OHD) and precocious puberty in girls. METHODS A total of 60 girls with central precocious...

introduction: vitamin d has an important role in maintaining human health. the main source of vitamin d production is skin exposure to sunlight. accordingly with the spread of apartment life culture, growth of industrial cities and the increase of air pollution; vitamin d deficiency and its implications is an important factor in the appearance of debilitating diseases in different age categorie...

Vitamin D deficiency is one of the major health problems that is unexpectedly prevalent in Iran. The ultraviolet (UV) rays of the sunlight are the most important source of vitamin D in humans. In contrast, environmental factors are one of the reasons for decrease in UV transmission to the earth which results in the reduction of vitamin D absorption. Since the role of environmental factors has b...