As Director of the Office of Scientific Research and Development, Dr. Vannevar Bush has coordinated the activities of some six thousand leading American scientists in the application of science to warfare. In this significant article he holds up an incentive for scientists when the fighting has ceased. He urges that men of science should then turn to the massive task of making more accessible o...

How do experienced users extract information from a complex visualization? We examine this question by presenting experienced weather forecasters with visualizations that did not show the needed information explicitly and examining their eye movements. We replicated Carpenter & Shah (1998) when the information was explicitly available on the visualization. However, when the information was not ...

The importance of socioeconomic position, measured at multiple levels (e.g., individual, household, area) and across the life course, for studying health disparities is now well recognized (1–7). Our multilevel study (8) reported that individual-based socioeconomic measures (IBSMs) and area-based socioeconomic measures (ABSMs) together capture birth weight inequalities that otherwise would have...

BACKGROUND Phase I trials have traditionally been designed to assess toxicity and establish phase II doses with dose-finding studies and expansion cohorts but are frequently exceeding the traditional sample size to further assess endpoints in specific patient subsets. The scientific objectives of phase I expansion cohorts and their evolving role in the current era of targeted therapies have yet...

in nutritional experiments the animals are kept in metabolic cage and are fed according to the planned interval times. a machine was designed and fabricated to feed the sheep every one or two hours. the machine operates with 220 volts electricity and the feed storing capacity is designed for three days feeding. the weight of sheep and type of feed determines the amount of feed required. by chan...