نتایج جستجو برای: γ r1 ifn
تعداد نتایج: 106906 فیلتر نتایج به سال:
Background: The prevalence of allergic diseases is increasing worldwide. The effective role of omega-3 fatty acids in the maturation of immune system and protection against atopic diseases has been well discussed. However, previous studies revealed conflicting results. This study was conducted to investigate the effect of fish oil consumption by nursing atopic mothers on the level of interferon...
peripheral, placental and cord cytokines profile in spontaneous labor and elective caesarean section
background: cesarean section delivery can lead to much maternal morbidity. different cytokines have been reported to be influenced by the mode of delivery. objective: to investigate the influence of mode of delivery on maternal, placental and cord sera of interferon gamma (ifn-γ), interleukin-4 (il-4) and interleukin-10 (il-10) levels. methods: these three cytokines were measured using elisa in...
BACKGROUND Traditionally, interferon-γ (IFN-γ) was regarded as a pro-inflammatory cytokine, however, recent reports suggested role of IFN-γ in immune tolerance. In our previous report, we could induce tolerance to male antigen (HY) just by male islet transplantation in wild type C57BL/6 mice without any immunological intervention. We tried to investigate the influence of IFN-γ deficiency on tol...
Background and Objective: Asthma is a common respiratory disease caused by acute and chronic bronchial inflammation. Clinical manifestations of the disease are closely related to genetics. IL-4 is a cytokine of TH2 lymphocytes, polymorphism in prompter region, C-589T, is associated with IL-4 production, while IFN-γ, is a cytokine of TH1, and A+874T polymorphism in interon 1 of IFN-γ is associat...
Abstract Epstein-Barr virus-positive gastric cancer [EBV (+) GC] is a distinct GC subtype with unique genetic and epigenetic aberrations. Here, we examined resected samples publicly available microarray data The Cancer Genome Atlas (TCGA) database to identify the mechanism underlying overexpression of PD-L1 in EBV GC. We found that high levels were caused by focal amplification CD274 . By contr...
cytokines have been introduced as critical inducers in the development of th subpopulations.cytokines like il-10 are involved in inducing regulatory t cells such as type 1 regulatory t (tr1) cells cells. il-22 is a member of il-10 family of cytokines, and il-28a is a member of ifn-γ family. in this study, cord blood mononuclear cells (cbmc) from normal healthy individuals were isolated by ficol...
Interferon-gamma (IFN-γ) is a pleiotropic cytokine that exerts anti-tumor and anti-osteoclastogenic effects. Although transcriptional and post-transcriptional regulation of IFN-γ is well understood, subsequent modifications of secreted IFN-γ are not fully elucidated. Previous research indicates that some cancer cells escape immune surveillance and metastasize into bone tissue by inducing osteoc...
background: the aim of this study was to determine the th1 and th2 serum cytokines, in patients with psoriasis and to com pare their cytokine levels with those of normal control subjects. methods: serum levels of interferon-gamma (ifn-γ), interleukin-2 (il-2), interleukin-4 (il-4), and interleukin-10 (il-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in...
زمینه و اهداف: مقاومت یا ایمنی سلولی در برابر عفونت توبرکولوز، بستگی به عملکرد لمفوسیت های T، که فعال کننده ماکروفاژهای از بین برنده مایکوباکتریوم های داخل سلولی اند، دارد. لمفوسیت های T از طریق ترشح شبکه ای از فاکتورهای محلول سایتوکاین ها، مسوول این روابط سلولی اند و طی سه دهه اخیر به طور گسترده مورد مطالعه قرار گرفته اند. اولین رخداد عفونت در میزبان با یک پاتوژن، پاسخ ایمنی ذاتی است که شامل ...
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