The article by Brenna and Spandonaro on interregional mobility for acute hospital care in Italy raises important issues concerning social and territorial equity in a healthcare system. Based on Regions and private providers’ strategic behavior, the hypothesis adopted to explain patient cross-border mobility (CBM), demonstrated by statistical analysis, may be further explored using qualitative m...

BACKGROUND Central pain in multiple sclerosis (MS) is common and often refractory to treatment. METHODS We conducted a single-center, 5-week (1-week run-in, 4-week treatment), randomized, double-blind, placebo-controlled, parallel-group trial in 66 patients with MS and central pain states (59 dysesthetic, seven painful spasms) of a whole-plant cannabis-based medicine (CBM), containing delta-9...

Abstract Experimental studies applying cognitive bias modification of attention (CBM-A) and interpretation (CBM-I) to reduce aggression have examined the effect modifying each in isolation. In order maximise potential impact on both biases symptom reduction, we whether a combined training procedure targeting (CBM-AI) combination would be more effective than alone. University students (17–35 yea...

INTRODUCTION Worry and rumination are two forms of repetitive thinking characterised by their negative content and apparently uncontrollable nature. Although worry and rumination share common features and have been conceptualised as part of a transdiagnostic repetitive negative thinking (RNT) process, it remains unclear whether they share the same underlying cognitive mechanisms. This multisess...

Coal bed methane (CBM) is generated primarily through the microbial degradation of coal. Despite a limited understanding of the microorganisms responsible for this process, there is significant interest in developing methods to stimulate additional methane production from CBM wells. Physical techniques including hydraulic fracture stimulation are commonly applied to CBM wells, however the effec...

The objective of condition based maintenance (CBM) is typically to determine an optimal maintenance policy to minimize the overall maintenance cost based on condition monitoring information. The existing work reported in the literature only focuses on determining the optimal CBM policy for a single unit. In this paper, we investigate CBM of multi-component systems, where economic dependency exi...