AIMS To determine the prevalence and risk factors for worsening renal function (WRF) among patients hospitalized for decompensated heart failure (HF) and the association with subsequent re-hospitalization and mortality. METHODS AND RESULTS We prospectively enrolled 299 patients across eight European countries (mean age 68, 74% men). HF was defined using the European Society of Cardiology crit...

BACKGROUND Renal impairment is a common comorbidity and the strongest risk factor for poor prognosis in acute decompensated heart failure (ADHF). In clinical practice, renal function is labile during episodes of ADHF, and often worsens after discharge. The significance of worsening of renal function (WRF) after discharge has not been investigated as extensively as baseline renal function at adm...

Surface temperature, precipitation, specific humidity and wind anomalies associated with the warm and cold phases of ENSO simulated by WRF and HadRM are examined for the present and future decades. WRF is driven by ECHAM5 and CCSM3, respectively, and HadRM is driven by HadCM3. For the current decades, the ECHAM5-WRF, CCSM3-WRF and HadRM simulations are broadly consistent with the observed warm-...

BACKGROUND Despite rapid clinical adoption of novel anticoagulants, it is unknown whether outcomes differ among patients with worsening renal function (WRF) taking these new drugs compared with warfarin. We aimed to determine whether the primary efficacy (stroke or systemic embolism) and safety (major bleeding and nonmajor clinically relevant bleeding) end points from the ROCKET AF trial (Rivar...

In this article we have configured the nested grid WRF v.3.6 model for the Caucasus region. Computations were performed using Grid system GE-01-GRENA with working nodes (16 cores+, 32GB RAM on each). Two particulate cases of unexpected heavy showers were studied. Simulations were performed by two set of domains with horizontal grid-point resolutions of 6.6 km and 2.2 km. The ability of the WRF ...

White-rot fungi (WRF) and their lignin modifying enzymes (LME) can degrade a wide range of trace organic contaminants (TrOC), which are suspected to cause adverse health effects in humans and other biota. Recent studies have successfully applied either whole-cell WRF or their extracellular culture extract to remove TrOC from the aqueous phase. TrOC removal by a WRF system is dependent on a rang...

Baseline renal function is a potent independent risk factor for adverse events after acute myocardial infarction (MI). Worsening renal function (WRF) has been shown to influence outcomes in the heart failure population, but its impact on cardiovascular risk in the post-MI period has not been well defined. For assessment of the prognostic importance of WRF, 2231 patients who had left ventricular...

The goal of this Masters project is to implement the WRF model with 3D variational assimilation (3DVAR) at MIT. A working version of WRF extends the scope of experimentation to mesoscale problems in both real and idealized scenarios. A state-of-the-art model and assimilation package can now be used to conduct science or as a benchmark to compare new methods with. The second goal of this project...