محاسبه دز جذبی در اندام انسان یکی از اولین گام‌­ها برای توسعه رادیوداروهای جدید است. هدف این مطالعه تخمین توسط ترکیب نوین نشاندار Cu-NODAGA-RGD-BBN64 بدین‌منظور ابتدا با تغییر پارامترهای مؤثر بر نشاندارسازی شرایط بهینه تهیه شد. پایداری پپتید هترودیمر بافر سالین فسفات (PBS) و سرم خون انسانی به مدت 12 ساعت ارزیابی پس آن، توزیع زیستی کمپلکس موش‌های حامل تومور تزریق مورد بررسی قرار گرفت. نهایت، اسا...

The solutions used to solve bi-level congestion pricing problems are usually based on heuristic network optimization methods which may not be able to find the best solution for these type of problems. The application of meta-heuristic methods can be seen as viable alternative solutions but so far, it has not received enough attention by researchers in this field. Therefore, the objective of thi...

background one-third of the world’s population is infected with mycobacterium tuberculosis. investigation of toll-like receptors (tlrs) has revealed new information regarding the immunopathogenesis of this disease. toll-like receptors can recognize various ligands with a lipoprotein structure in the bacilli. toll-like receptor 2 and tlr-4 have been identified in association with tuberculosis in...

بإنتهاء الحرب العالمية الأولى عام 1918 م ، تكون بريطانيا قد خرجت من منتصرة إلا أنها كانت تعاني أزمة اقتصادية ومالية صعبة للغاية وجيش مُتعَب يحتاج إلى إعادة تأهيل . وقوات بحرية شبه مُدَمرة وفقدت ثلثي سفنها ومُعداتها ومدن مُهدمة وطرق وجسور خَرِبة وعلى الرغم ذلك فقد بسطت سيطرتها على مستعمراتها في القارة الهندية والخليج العربي وبلاد فارس والعراق وفلسطين وشرق الأردن وعدن ومضيق باب المندب وأجزاء الصومال والب...

the importance of the role played by bacteria in the pathogenesis of pulpal and apical disease has been established. one of the characteristics of apical periodontitis is apical bone resorption, which is due to apical immune response to bacterial infection. recently, novel bacterial complex lipid called phosphorylated dihydroceramides has been discovered to be of inflammatory activators. the ba...

it has been suggested that single nucleotide polymorphisms (snps) in genes involved in toll-like receptors (tlrs) pathway may exhibit broad effects on function of this network and might contribute to a range of human diseases. however, the extent to which these variations affect tlr signaling is not well understood. in this study, we adopted a bioinformatics approach to predict the consequences...

the congestion pricing has been discussed as a practical tool for traffic management on urban transport networks. the traffic congestion is defined as an external diseconomy on the network in transport economics. it has been proposed that the congestion pricing would be used to reduce the traffic on the network. this paper investigates the cordon-based second-best congestion-pricing problems on...