The aim of the study was to determine temporal TGFB1, TGFB2 and TGFB3 gene expression profiles in the anterior lens capsule of paediatric patients with posttraumatic cataract. The patient group comprised 22 children selected with a fragment of anterior lens capsule obtained during elective cataract surgery and sampled for molecular ana...

Outcome of patients (pts) w/ stage I node neg HER2+ treated wkly paclitaxel x 12 doses and trastuzumab 1yr is excellent (10yr RFS 96%). Therefore, trials to de-escalate chemo use targeted therapy alone are underway. Zanidatamab a novel, humanized, bispecific, immunoglobulin G isotype 1-like, monoclonal antibody directed against the juxtamembrane extracellular domain (ECD4) dimerization (ECD2) H...

Background: Recent research on several DNA fragments covering open reading frames (ORF) 1-37 shows a new genetic marker in ORF 6 which is specific for differentiating wild-type varicella-zoster virus (VZV) strains from Oka varicella vaccine strain. On the other hand, herpes simplex virus (HSV) genome analysis by restriction enzymes is used to differentiate types one and two of the virus and eve...

ObjectivesUndetectable or low-level hepatitis B virus (HBV) DNA and drug resistance mutations in patients may increase the risk of HBV transmission cause active viral replication other clinical problems. Here, we established a highly sensitive practical method for detection using polymerase chain reaction (PCR) -based CRISPR-Cas13a system (referred to as PCR-CRISPR) evaluated its capability sam...

background and objectives: pcr is a sensitive assay and could be used as an accurate diagnostic method for detecting various types of microorganisms' genome in low concentration in biological specimens. the demand for sensitive, rapid, safe and easy detection of pcr products has led researchers to a combination of this method with elisa. materials and methods: conserved sequences were selected ...

Abstract The HPPD gene is one of the genes that actively involved in biosynthesis tocopherol, which main component Vitamin E. Sunflower raw materials for natural medicine since their oil contains vitamin To obtain complete information regarding whole sequences 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) sunflower accession HA1, exon region needs to be identified using a PCR-based method. One fac...