BACKGROUND Prone position and PEEP can both improve oxygenation and other parameters, but their interaction has not been fully described. Limited data directly compare selection of mechanically "optimal" or "best" PEEP in both supine and prone positions, either with or without changes in chest wall compliance. To compare best PEEP in these varied conditions, we used an experimental ARDS model t...

Oxygen is an essential part of the most important metabolic pathways in aerobic organisms. Oxygen delivery is merely dependent on blood, rendering blood loss a devastating event. Traumatic pre-hospital liver bleeding is a major cause of early trauma deaths in human and animals, with no established therapeutic method yet. Increasing intra-abdominal pressure (IAP) has been shown to reduce liver b...

INTRODUCTION We hypothesized that mechanical ventilation per se increases abdominal edema and inflammation in sepsis and tested this in experimental endotoxemia. METHODS Thirty anesthetized piglets were allocated to one of five groups: healthy control pigs breathing spontaneously with continuous positive pressure of 5 cm H2O or mechanically ventilated with positive end-expiratory pressure of ...

Expulsive maneuvers (EMs) caused by simultaneous contraction of diaphragm and abdominal muscles shift substantial quantities of blood from the splanchnic circulation to the extremities. This suggests that the diaphragm assisted by abdominal muscles might accomplish ventilation and circulation simultaneously by repeated EMs. We tested this hypothesis in normal subjects by measuring changes (Δ) i...

OBJECTIVE This study aims to explore the usage of intraocular pressure measurements as the early indicator of the increase in intra-abdominal pressure. METHODS In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients. The control group (Group C) was not subjected to laparoscopic intervention. Laparoscopic surgery w...

OBJECTIVES To develop a direct method for measuring intra-abdominal pressures in the standing horse, identify a reference interval for direct intra-abdominal pressures, compare these pressures to indirect intra-abdominal pressures measured from the bladder, and determine the optimal bladder infusion volume for indirect pressure measurement. DESIGN Prospective, experimental study. SETTING A ...

abdominal aortic coarctation is an extremely rare vascular pathology. its etiology can be congenital or acquired. here we present a case of acquired infrarenal abdominal coarctation in a 66-year-old woman who complained of low back and legs pain. she had no signs of resting lower limb ischemia, with diminished distal pulses and normal blood pressure in upper and lower extremities. magnetic reso...

Introduction Central venous pressure (CVP) is frequently used to guide fluid therapy, although there are confounders of CVP like intra-abdominal pressure (IAP) and mechanical ventilation. Despite a large number of studies on the interactions of intra-abdominal pressure, mechanical ventilation and CVP there are few studies investigating the impact of both major confounders of CVP in the same set...