BACKGROUND & OBJECTIVES Leishmaniasis is a parasitic disease transmitted by sand flies. Many investigations are performed to find an effective and safe treatment for leishmaniasis. In this study, we evaluated the efficacy of herbal extracts of Thymus vulgaris (Thyme) and Achillea millefolium (Yarrow), propolis hydroalcoholic extract and systemic glucantime against cutaneous leishmaniasis in Bal...

The species of genus Achillea, particularly those belonging to the Achillea millefolium group have received a lot of attention so far, due to their use in traditional medicine. Among the numerous chemical compounds isolated from the A. millefolium species, the sesquiterpene lactones are usually one of the major constituents (Seaman, 1982). Continuing our chemotaxonomic examination of Bulgarian ...

Statistical review: Yes, but I do not feel adequately qualified to assess the statistics.

Achillinin A (2β,3β-epoxy-1α,4β,10α-trihydroxyguai-11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LC-kj and QG-90 cells with 50% inhibitory concentration (IC(50)) values of 5.8, 10 and 0.31 µM, respectively.