Background Andrographolide (AG), a compound with low water solubility, possesses various pharmacological activities, particularly anti-inflammatory activity. However, its low oral bioavailability is a major obstacle to its potential use. This study developed and optimized an AG-loaded nanoemulsion (AG-NE) formulation to improve AG oral bioavailability and its protective effects against inflamma...

The effect of chemically synthesized selenium (Se) nanocomposites (NCs) based on the natural polymer matrices arabinogalactan (AG), carrageenan (CAR), and starch (ST) potato tuber traits, storage, crop structure was studied in a field trial. Parental tubers were sprayed by Se/AG NC, Se/ST Se/CAR NC 14 days before planting field. results showed that increased number weight first generation (F1) ...

The green synthesis of metallic nanoparticles is an active research area in nanotechnology. In the present study, antioxidant potential, total reducing capacity and silver nanoparticles (Ag NPs) synthetic potential of methanolic leaf extracts of seven plant species were evaluated and compared. Antioxidant capacity, expressed as µmol Trolox equivalents g-1 DW (µmol TE g-1 DW), ranged from 116.0 ...

Experiments were conducted in a laboratory and an outdoor mesocosm system to evaluate the liquid AVAST!® fluridone formulation for control of Eurasian watermilfoil (Myriophyllum spicatum). In addition, physiological assays were used to monitor plant injury during herbicide exposure. Eurasian watermilfoil was planted in 52-L aquaria, grown to precanopy condition (21 days), then dosed with 0, 10,...

In lowland Amazonian rainforests, specific ants collect seeds of several plant species and cultivate them in arboreal carton nests, forming species-specific symbioses called ant-gardens (AGs). In this obligate mutualism, ants depend on the plants for nest stability and the plants depend on ant nests for substrate and nutrients. AG ants and plants are abundant, dominant members of lowland Amazon...

Since the use of seed priming agents to reduce the potential toxicity of AgNPs has not been explored, we evaluated the combined effects of 0.1 mM salicylic acid (SA) and 0.1 mM nitric oxide (NO) on responses of Hypericum perforatum plants to Ag-induced stress. The results of growth parameters together with measurement of malondialdehyde (MDA) revealed that exposure to AgNPs or AgNO3 caused more...

Alfuzosin, a selective alpha-1a antagonistis is the most recently approved AARAS, with limited cardiac toxicity and exclusively used for lower urinary tract syndromes (LUTS). In order to reduce pill burden and better patient compliance modified release (MR) formulations have been developed. Alfuzosin MR tablet was developed by the use of hot-melt granulation techniques using mono- and diglyceri...

Biofabrication by using fungi is an exciting recent interest to develop an eco-friendly production of metallic nanoparticles (NPs) for pharmaceutical applications. This study aimed to synthesize and characterize gold (Au) and silver (Ag) NPs by using Penicillium simplisimum. The fungus was grown in fluid czapek dox broth on shaker at 28 ºC and 200 rpm for ten days. Then the supernatant was...

600 seven day-old ross broiler chicks were tested in a factorial experiment (2×5) with two levels of oil (three and six percent) and five levels of soybean oil and soapstock (100:0, 75:25, 50:50, 25:75 and 0:100) with four replicates. rations were isocaloric and isonitrogenus. the chicks of the rations with three percent fat had higher weight gain and lower feed intake and feed: gain ratio (p