Portulaca quadrifida Linn. has been evaluated for its hepatoprotective activity in Swiss albino mice using the mercury induced hepatotoxicity. The ethanolic extract showed remarkable activity against mercury-induced hepatotoxicity as judged from biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and levels of lipid...

This study was performed to determine the potential hepatoprotective and anti-inflammatory effects of the microalgae pigment phycocyanin in galactosamine-induced acute liver damage in rats. Phycocyanin (50-200 mg kg i.p) was administered one hour before the galactosamine (600 mg kg i.p) and the blood was extracted 24 hours later to determine alanine amino transferase (ALT), aspartate amino tran...

The molar conductivity data of 1-butyl-3-methylimidazolium salicylate, [BMIm][Sal] as an active pharmaceutical ingredient ionic liquid (API-IL) have been determined in water and aqueous solutions of amino acids, glycine and L-alanine at T= (288.15 to 318.15) K. The molar conductivity data were analyzed by low concentration Chemical Model (lcCM) and limiting molar conductivities ( ), ion associa...

This pilot study was designed to establish the effect of long term alpha interferon treatment in haemophilia patients with chronic hepatitis C. Overall, three of eight (37.5%) patients showed a complete response, three of eight (37.5%) a transient response, and two of eight (25.0%) no response. HCV-RNA detection by polymerase chain reaction was more sensitive in detecting relapse than alanine a...

Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV-C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detect...

The primary control of autophagically mediated proteolysis in perfused rat liver is carried out via two alternate mechanisms in response to specific regulatory amino acids. One (L) elicits direct inhibition at low and high plasma levels, but requires a co-regulatory amino acid to express inhibition at normal concentrations. The second (H) is ineffective at normal levels and below, but active at...

Abbreviations: MPN: Myeloproliferative Neoplasms; PV: Polycythemia Vera; ET: Essential Thrombocythemia; PMF: Primary Myelofibrosis; CBC: Complete Blood Count; SVT: Splanchnic Veins Thrombosis; PVT: Portal Vein Thrombosis; BCS: Budd Chiari Syndrome; AST: Aspartate Amino Transferase; ALT: Alanine Aminotransferase; WBC: White Blood Cell count; CT: Computed Tomography; Ig: Immunoglobulin; ADP: Aden...

Aim: To evaluate the effect of different levels of High Bentonite on growth performance, organ weight and serum biochemistry in broiler fed on diets containing aflatoxin. Materials and Methods: A total of 360 day-old commercial broiler chicks were divided at random into 8 dietary treatment groups of 42 chicks each having 3 replicates. Dietary levels of aflatoxin (0.5 ppm) and High-grade bentoni...

A total of 540 one-day old male broilers Ross 308 were allocated to 6 treatments in a completely randomized designed with a 2×3 factorial arrangement (aflatoxin B1 (AFB1) and probiotics) with 6 replicates and 15 birds in each. Factors include aflatoxin B1 (control, 500 ppb) and probiotics (control, 108 cfu/mL Bacillus sp. MBIA2.40, 0.2 g Gallipro per kg). Results showed that adding 500 ppb AFB1...

BACKGROUND Petroselinum crispum, a bright green biennial shrub is widely used traditionally as a food additive and herbal remedies for many ailments. This study therefore aimed to assess the toxic effects of its leaf extract using some biochemical, haematological parameters. METHODS The toxic effects were assessed by quantifying liver enzymes such as serum aspartate amino transferase (AST), a...