UNLABELLED BACKGROUND Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their ...

Background: Software product lines and Agile methods have been an effective solution for dealing with the growing complexity of software and handling competitive needs of software organizations. They also share common goals, such as improving productivity, reducing time-to-market, decreasing development costs and increasing customer satisfaction. There has been growing interest in whether the i...

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in cancer development through stimulation of cell survival, proliferation, migration, and angiogenesis. Irreversible degradation of S1P is catalyzed by S1P lyase (SPL). The human SGPL1 gene that encodes SPL maps to a region often mutated in cancers. To investigate the effect of SPL deficiency on cell survival and tran...

Hunter, Emily, "Transcriptional Regulation of Notch target E(spl)mγ by Tramtrack69 and Putzig in Drosophila melanogaster" (2012). Abstract The Notch pathway plays an important role during development by regulating whether a cell takes on a neuronal or non-neuronal cell fate in the peripheral nervous system of Drosophila melanogaster. When Notch signaling is present in a cell, the cell is preven...

The increasing complexity and cost of softwareintensive systems has led developers to seek ways of reusing software components across development projects. One approach to increasing software reusability is to develop a Software Product-line (SPL), which is a software architecture that can be reconfigured and reused across projects. Rather than developing software from scratch for a new project...

In this paper, synthetic jet actuators (SJAs) with three different orifice shapes (circular, square, and slot) the same cross-section area were investigated. The SJA efficiency (SJ) Reynolds number calculated based on time-mean reaction force measurement. momentum velocity was measured hot-wire anemometry additionally, sound pressure level (SPL) measured. equal maximally to 5.3% for each shape,...

Self-paced learning (SPL) is a recently raised methodology designed through simulating the learning principle of humans/animals. A variety of SPL realization schemes have been designed for different computer vision and pattern recognition tasks, and empirically substantiated to be effective in these applications. However, the investigation on its theoretical insight is still a blank. To this is...