n3 polyunsaturated fatty acids have been reported to have anti-carcinogenic effects on mammalian carcinomas. n3 fatty acids occur in high concentrations in marine oils, especially shark liver oils. Several reports have indicated an extremely low incidence of cancer in sharks, although other reports indicate carcinogenesis in some shark species. It has been hypothesised that n3 fatty acids and o...

One of the main etiological factors in development some malignant tumours is presence chronic inflammatory processes. A number biomedical studies have confirmed anticarcinogenic effect anti-inflammatory drugs with respect to colon cancers. In addition, biologically active substances present medicinal plants been found exhibit both anti-carcinogenic and antioxidant activity. this paper, we inves...

Background and objectives: Phyllanthus emblica L. (Phyllanthaceae), commonly known as Indian gooseberry, is an endemic plant to the tropical and subtropical areas in china, India and Thailand. The plant is extensively used in Chinese, Ayurveda, and traditional Persian medicine (TPM). In addition, there are numerous reports on pharmacological and clinical activities of ...

Objective: Cancer arises as a result of the failure mechanisms controlling normal division in group cells. It is known that some new synthesis compounds intended for use cancer treatment have anti-fungal, anti-bacterial, anti-carcinogenic effects. In this study, it was aimed to apply newly synthesized B-108 compound A-549 cell line and then investigate effect on ERCC1 gene expression profile.&#...

duction of tumors by imbedding plastic films sub cutaneously in rodents, we have also conducted some investigations on the effect of similar im bedding of metal foils. This has included silver, tin, tantalum, vitallium (an alloy of chromium, cobalt, and molybdenum), and stainless steel. The experiments with the first two metals are corn plete, and final results can be recorded. Although the exp...

Aneuploidy has recently been proposed as an initiating event for carcinogenesis. There is significant evidence that carcinogenic metals induce aneuploidy. Here we review the mechanisms for how carcinogenic metals may induce aneuploidy and the evidence that carcinogenic metals induce an aneugenic effect which can destabilize the genome leading to genomic instability and cancer.