Two hundred coronary arteriograms and left ventriculograms of patients having significant coronary artery disease were reviewed. Collateral circulation was seen only when the degree of arterial narrowing exceeded 90%. Ten different collateral pathways were noted in patients having right coronary obstruction; seven different pathways were noted in left anterior descending obstruction; five diffe...

1. The effect of breathing a mixture of 5-6% carbon dioxide in air was examined in seven patients with obstructive bronchitis and in eight patients with lung disease but without bronchial obstruction. 2. Hyperventilation during CO2 breathing was less marked in patients with bronchial obstruction than in the others. Cardiac output did not change in patients with airways obstruction but rose in t...

Obstructive sleep apnea (OSA) is a common disorder of upper airway obstruction during sleep. The effects of intermittent upper airway obstruction include alveolar hypoventilation, altered arterial blood gases and acid-base status, and stimulation of the arterial chemoreceptors, which leads to frequent arousals. These arousals disturb sleep architecture and cause hypersomnolence. Chronic intermi...

A 72-year-old female presented rapidly developing ischemia of the skin and subcutaneous tissue antero-medial aspect a thigh. An atypical clinical manifestation led to delayed diagnosis treatment that resulted in development large loss anteromedial Endovascular recanalization recurrent occlusion ilio-femoral segment with rotational thrombectomy together multi-step local surgical healing lesion.

Two hundred sixty-two patients with 50% or greater obstruction of at least one coronary artery on the initial study underwent recatheterization 2-182 months later and were evaluated for progressive arterial changes. Progression was considered present if (1) a change from less than total obstruction to total obstruction occurred in any vessel; (2) a change from 70% or less to 90% or more occurre...

The time constant of the pulmonary circulation, or product of pulmonary vascular resistance (PVR) and compliance (Ca), called the RC-time, has been reported to remain constant over a wide range of pressures, etiologies of pulmonary hypertension, and treatments. We wondered if increased wave reflection on proximal pulmonary vascular obstruction, like in operable chronic thromboembolic pulmonary ...

A 22-year-old competitive female cyclist complained of cough, chest tightness, and wheeze during high-intensity exercise that had previously been diagnosed as exercise-induced bronchospasm (EIB). A loud stridor, a sensation of her "throat closing," and severe dyspnea developed during maximal cycling exercise with concomitant reductions in both inspiratory and expiratory flow rates. A decrease o...