Saeed Changizi Ashtiyani

Department of Physiology, Arak University of Medical Sciences, Arak, Iran

[ 1 ] - A quick overview on some aspects of endocrinological and therapeutic effects of Berberis vulgaris L.

Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry. The most important compounds i...

[ 2 ] - Therapeutic effects of curcumin on the functional disturbances and oxidative stress induced by renal ischemia/reperfusion in rats

Objectives: Curcumin has anti-inflammatory and antioxidative properties. The objective of this study was to investigate the therapeutic effects of curcumin on functional disturbances, oxidative stress, and leukocyte infiltration induced by renal ischemia/reperfusion (I/R). Materials and Methods: Animals were randomly divided into 9 groups. The groups with 24-h reperfusion consisted of sham-24h,...

[ 3 ] - Comparison between effects of different doses of Melissa officinalis and atorvastatin on the activity of liver enzymes in hypercholesterolemia rats

Objectives: Liver is one of the most sensitive tissues to oxidant damage. Hence, the present study was conducted to compare the effects of Melissa officinalis (MO) extract and Atorvastatin on the activity of liver enzymes in rats. Materials and Methods: In this experimental study, 60 male Wistar rats were selected and allocated to six groups (n=10). The control group received a normal diet, sha...

[ 4 ] - The effects of Artemisia aucheri extract on hepatotoxicity induced by thioacetamide in male rats

Objective: Liver is an important organ that is exposed to many oxidant and carcinogenic agents, thus antioxidant compounds are beneficial for liver health. Artemisia contains flavonoid compounds and anti-diabetic, antioxidant, and anti-inflammatory properties. Due to possessing terpene and sesquiterpene compounds, this plant has antioxidant properties. This study was done to investigate the eff...

[ 5 ] - مروری گذرا بر آرا و نظریات رازی، ابن سینا و جرجانی در باب باروری و ناباروری

  Introduction : Infertility is a serious health problem in approximately 10-15% of couples in reproductive ages suffering from this problem. Depending on the cause of infertility, there are a variety of diagnostic and therapeutic views. The aim of this study was to determine the scientific views of Islamic-Iranian physicians (Rhazes, Ibn sina and Jorjani) on infertility comparing with modern m...

[ 6 ] - بررسی اثر عصاره بخش‌های هوایی گیاه خوشاریزه بر تست‌های عملکردی کبدی و کلیوی در رت‌های چاق هیپرکلسترولمی شده

Introduction: Obesity and its complications such as hypertension, fatty liver, type 2 diabetes and kidney failure, can be mentioned as the main life-threating elements. Therefore, this study aimed to evaluate the effect of air parts extract of Echinophora platyloba.L (EP) on changes in body weight as well as liver and kidney function tests in hypercholesterolaemia obese rats. Methods: In thi...

[ 7 ] - بررســــی اثر عصاره‌ی هیدروالکلــــی گیــــاه بادرنجبویه (Melissa officinalis .L) بر میزان شاخص عملکرد کلیوی و آنزیمهای کبدی در رتهای دیابتی شده

مقدمه: بیماری دیابت با طیف وسیعی از اختلالات کلیوی و کبدی همراه است. هدف این مطالعه، مقایسه تاثیر عصاره‌‌ی الکلی بخش‌های هوایی بادرنجبویه بر شاخص‌های عملکرد کبدی و کلیوی در رت‌های دیابتی شده بود. مواد و روش‌ها: در این مطالعه، 35 سر رت نژاد ویستار به 5 گروه بدین شرح تقسیم‌ شدند: شاهد، شاهد دیابتی که روزانه نرمال سالین دریافت می‌کردند و گروه‌های دیابتی که به ترتیب با عصاره‌ی الکلی بادرنجبویه در م...

[ 8 ] - Effects of selenium nanoparticles on kidney and liver functional disorders in streptozotocin-induced diabetic rats

Introduction: Diabetes mellitus, as a chronic metabolic disease, is associated with a wide range of kidney and liver disorders. The goal of this study was to indicate the effects of selenium nanoparticles on the function of kidney and liver enzymes in stereptozocin induced diabetic rats. Methods: In this study, 35 male wistar rats were divided into five groups (n=7): control, diabetic control a...

[ 9 ] - Swertia longifolia Boiss has beneficial effects on hepatic and renal functions in diabetic rats

Introduction: Diabetes is a multifactorial syndrome with high prevalence which may induce serious disorders in the body organs like the liver and kidney. This study aimed to compare the effects of the alcoholic extract of the aerial parts of Swertia longifolia Boiss on blood glucose, lipid profiles and liver and kidney function tests in streptozotocin-induced diabetes. Methods: Thirty five male...

[ 10 ] - اثرات ال- کارنیتین و آلفا- توکوفرول بر روی نقص دفع اسید ناشی از انسداد حاد میزنای در رت‌های بیهوش

Background: Ureteral obstruction has been shown to induce renal oxidative stress, suppressed energy metabolism and defected acid excretion. This study was aimed to examine the improving effects of L-carnitine, a facilitating cofactor for mitochondrial oxidation of fatty-acids as well as a scavenger of free-radicals, and -tocopherol as the most potent antioxidant on these renal disorders at ear...