Amyloid-β (Aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in Alzheimer’s disease pathology.Uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. Aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

Proper planning of assembly lines is one of the production managers’ concerns at the tactical level so that it would be possible to use the machine capacity, reduce operating costs and deliver customer orders on time. The lack of an efficient method in balancing assembly line can create threatening problems for manufacturing organizations. The use of assembly line balancing methods cannot balan...

This paper presents an integrated assembly and motion planning system to recursively find the assembly sequence and motions to assemble two objects with the help of a horizontal surface as the supporting fixture. The system is implemented in both assembly level and motion level. In the assembly level, the system checks all combinations of the assembly sequences and gets a set of candidates. The...

The typical problems facing garment manufacturers are long production lead time, bottlenecking, and low productivity. The most critical phase of garment manufacturing is the sewing phase, as it generally involves a number of operations or for the simple reason that it’s labor intensive. In assembly line balancing, allocation of jobs to machines is based on the objective of minimizing the workfl...

self-assembly of densely packed zno nanorods were grown on porous silicon (ps) substrate by low-temperature chemical bath deposition. the structural and optical properties of the obtained zno nanostructures on ps substrate were systematically studied. the strong and sharp (002) peak compared with other peaks in the x-ray diffraction (xrd) indicated thatzno nanorods formed with superior orientat...

Atlas is a suite of programs developed for assembly of genomes by a "combined approach" that uses DNA sequence reads from both BACs and whole-genome shotgun (WGS) libraries. The BAC clones afford advantages of localized assembly with reduced computational load, and provide a robust method for dealing with repeated sequences. Inclusion of WGS sequences facilitates use of different clone insert s...