We consider two semi-online scheduling problems on a single batch (processing) machine with jobs’ nondecreasing processing times and jobs’ nonincreasing processing times, respectively. Our objective is to minimize the makespan. A batch processing machine can handle up to B jobs simultaneously. We study an unbounded model where B = ∞. The jobs that are processed together construct a batch, and a...

We consider the problem of scheduling n jobs onm identical parallel batching machines. Each job is characterized by a release time and a processing time. Each machine can process up to B (B < n ) jobs as a batch simultaneously. The processing time of a batch is equal to the largest processing time among all jobs in the batch. The objective is to minimize the maximum completion time (makespan). ...

The Measurement and Control Engineering Center (MCEC), a National Science Foundation Industry/University Cooperative Research Center (I/UCRC), is a cooperative venture among Oklahoma State University, The University of Tennessee, Oak Ridge National Laboratory, the National Science Foundation, and numerous industrial partners. Current research efforts include two projects where opportunities for...

Introduction Nowadays, single-use bioreactors are widely accepted in pharmaceutical industry. This is based on shorter batch to batch times, reduced cleaning effort and a significantly lower risk of cross contaminations [1,2]. One large field of the application of single-use bioreactors is the seed train cultivation of mammalian cells [1]. The focus is further extended to perform state of the a...

Xanthan gum is an extracellular hetero polysaccharides of many industrial applications and produced by Xanthomonas campestris. This biopolymer is produced as extracellular product in submerged fermentation system. The production of xanthan was influenced by the concentration in glucose in medium. The maximal volumetric production of 17.9 g L was obtained in 80 g L glucose culture in shake flask...

There are relatively few industrial applications of process systems to the specialty batch process industry (as compared to bulk continuous or even bulk batch process industry). However, inherent flexibility of these processes can be exploited to increase productivity and product quality. This study is based on a real industrial example of fed-batch polymerisation of ethylene oxide with a base ...

In a large number of industrial semi-batch reactor applications, a single reaction takes place in the reactor and the operational objective is to compute the optimal feed rate of reactants and the optimal batch temperature that optimizes an objective function at the end of a fixed batch time. In this work, it is shown that the optimal operating policy can be split into several time intervals. A...

We consider an online scheduling problem in a parallel batch processing system with jobs in a batch being allowed to restart. Online means that jobs arrive over time, and all jobs’ characteristics are unknown before their arrival times. A parallel batch processing machine can handle up to several jobs simultaneously. All jobs in a batch start and complete at the same time. The processing time o...