نتایج جستجو برای: benzyl thio
تعداد نتایج: 12199 فیلتر نتایج به سال:
A novel series of azolylalkylthio, -sulfoxy, and-sulfonyl compounds was designed, synthesized, and evaluated for antipicornaviral activity. Two compounds (4i and 4 1) exhibited significant activity against various serotypes of human rhinovirus (HRV). It was found that incorporation of hydrophobic azoles such as 3-methylisoxazole or 4-methylthiazole led to increased activity. In addition, ac...
Whereas inorganic arsenic is classified as a human carcinogen, risks to human health related to the presence of arsenosugars in marine food are still unclear. Since studies indicate that human inorganic arsenic metabolites contribute to inorganic arsenic induced carcinogenicity, a risk assessment for arsenosugars should also include a toxicological characterization of their respective metabolit...
This study investigates the identity of two unexpected arsenic species found separately in a number of urine samples sent to the Health and Safety Executive's Health and Safety Laboratory for arsenic speciation (arsenobetaine, AB; arsenite, As3+; arsenate, As5+; monomethylarsonic acid, MMA5+; and dimethylarsinic acid, DMA5+). Micro liquid chromatography coupled to inductively coupled plasma mas...
Liver inflammation is closely associated with metabolic syndrome. Oxidative stress plays a synergistic role in inflammation by activating nuclear factor kappa B (NF-κB) signaling in the liver. Therefore, substantial efforts have been made to develop compounds that inhibit the generation of oxidative stress and activation of NF-κB. We synthesized twenty-six novel 5-(substituted benzyl)-2-oxo- an...
Newly synthesized tocainide analogs were tested for their state-dependent affinity and use-dependent behavior on sodium currents (INa) of adult skeletal muscle fibers by means of the Vaseline-gap voltage clamp method. The drugs had the pharmacophore amino group constrained in position alpha [N-(2,6-dimethylphenyl)pyrrolidine-2-carboxamide (To5)] or beta [N-(2,6-dimethylphenyl)pyrrolidine-3-carb...
BiFeO3 (BFO), Bi0.86Sm0.07Eu0.07FeO3 (BSEFO), and Bi0.86Sm0.07Cd0.07FeO3 (BSCFO) nano powders were prepared by the sol-gel combustion method and the catalytic performances were evaluated in the acetylation reaction of benzyl alcohol. The physical chemical properties of the catalysts were character...
In this study, TiO2-10%wt. carbon nanotube (CNT) nanocomposite powders were synthesized by sol-gel method at various hydrolysis rate affected by different reaction agents of acetyl acetone and benzyl alcohol. Crystallization of TiO2 was then achieved through calcination at 400 °C. The properties of nanocomposite powder investigated by scanning electron microscopy, X-ray diffraction and diffuse ...
a novel series of azolylalkylthio, -sulfoxy, and-sulfonyl compounds was designed, synthesized, and evaluated for antipicornaviral activity. two compounds (4i and 4 1) exhibited significant activity against various serotypes of human rhinovirus (hrv). it was found that incorporation of hydrophobic azoles such as 3-methylisoxazole or 4-methylthiazole led to increased activity. in addition, activi...
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