PURPOSE To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME). METHODS Forty-two rabbits (2.5-4.5 Kg) were randomly allocated into seven groups of six animals each: SHAM- surgical treatment alone; Bolus Control Group - 3 mL-intravenous (IV) bolus of saline; Continuous Infusion Contro...

AIM To compare bolus insulin delivery patterns during closed-loop home studies in adults with suboptimally [HbA1c 58-86 mmol/mol (7.5%-10%)] and well-controlled [58 mmol/mol (< 7.5%)] Type 1 diabetes. METHODS Retrospective analysis of daytime and night-time insulin delivery during home use of closed-loop over 4 weeks. Daytime and night-time controller effort, defined as amount of insulin deli...

Introduction: Tricyclic antidepressants (TCAs) are widely used in psychiatric and medical conditions and are a major cause of drug overdoses and fatal poisonings in many contries. Sodium bicarbonate administration is widely recommended as the first line treatment in TCAs intoxication but the best method of its administration has not been yet established therefore, we decided to compare the ef...

Introduction: Background: Radiotherapy of parotid tumors is achieved by different radiotherapy techniques. So they deliver the dose to organs at risk such as contralateral parotid, temporal lobe & spinal cord. The consequences of high dose to OARs are xerostomia, Temporal lobe necrosis and loss of hearing. Purpose: The aim of this study was to compare different treatment tech...

Introduction: Estimates of myocardial blood flow (MBF) from first-pass contrast-enhanced cardiac magnetic resonance (CMR) imaging require accurate measurement of the arterial input function (AIF) from the left-ventricular (LV) blood pool. Both dual-bolus [1] and dual-sequence [2,3] CMR methods have been proposed to maintain the linearity of the LV signal during the contrast passage. Several stu...

Dry matter intake (DMI) is a primary determinant of milk production in grazing dairy cows and an ability to measure the DMI individual would allow herd managers formulate supplementary rations that consider amount nutrients ingested from grass. The 2 related aims this experiment were define mean number swallowed boli mass Holstein-Friesian cattle offered variety forages commonly fed industry so...

PURPOSE: A wide variation in the use of bolus has been observed in postmastectomy radiotherapy (PMRT), which affects dose delivery to skin and may have an impact on locoregional recurrence. However, even treatment planning systems (TPSs) with advanced algorithms do not provide accurate dosimetry in the buildup region. This study aims to perform in vivo measurements of the chest wall (CW) skin d...

BACKGROUND Mathematical modeling of cardiovascular magnetic resonance perfusion data allows absolute quantification of myocardial blood flow. Saturation of left ventricle signal during standard contrast administration can compromise the input function used when applying these models. This saturation effect is evident during application of standard Fermi models in single bolus perfusion data. Du...

During feeding, solid food is chewed and propelled to the oropharynx, where the bolus gradually aggregates while the larynx remains open and breathing continues. The aggregated bolus in the valleculae is exposed to respiratory airflow, yet aspiration is rare in healthy individuals. The mechanism for preventing aspiration during bolus aggregation is unclear. One possibility is that alterations i...