‎ Haleh‎ Talaie

Toxicological Research Center, Department of Clinical Toxicology, Loghman- Hakim Hospital, Shahid ‎Beheshti University of Medical Sciences, Tehran, Iran.‎

[ 1 ] - Methicillin Resistant Staphylococcus Aureus in Ventilator Associated ‎Pneumonia in Toxicological Intensive Care Unit

Background: Methicillin resistant Staphylococus Aureus (MRSA) is a cause of ‎nosocomial infections at intensive care unit (ICU), which imposes a high mortality and ‎morbidity on the health care systems.‎ The objective of this study was to evaluate the role of MRSA in patients with clinically ‎suspected ventilator associated pneumonia (VAP) in toxicological ICU admitted ‎patients.Methods: This ...

[ 2 ] - Prevalence of Class 2 Integrons in Multidrug-Resistant Acinetobacter Baumannii in Toxicological ICU Patients in Tehran

Background: Acinetobacter baumannii is an important opportunistic pathogen which causes complications in hospitalized patients, especially those in ICU. The aim of this study was to determine the frequency of class 1 and 2 integrons in multi-drug resistance A. baumannii and to investigate the association between the presence of integrons and antibiotic resistance patterns. Methods: A total of...

[ 3 ] - Alteration of Serum Levels of Interlukin 1 and Tumor Necrosis Factor in Depression Independent of Treatment or Overdose of Tricyclic Antidepressants

Introduction: Pro-inflammatory cytokines, such as IL-1b and TNF- α have been suggested to be involved in the pathophysiology of depression. Tricyclic antidepressants (TCAs) are also thought to influence immune functions and concentrations of cytokines. The aim of this study was to evaluate the status of serum IL-1b and TNF-α in depressed patients who were treated, not treated, or poisoned wit...

[ 4 ] - The Effect of Adding Sodium Bicarbonate Drip Infusion to Its Bolus Administration in Patients with Tricyclic Antidepressant Poisoning: A Randomized Clinical Trial

Introduction: Tricyclic antidepressants (TCAs) are widely used in psychiatric and medical conditions and are a major cause of drug overdoses and fatal poisonings in many contries. Sodium bicarbonate administration is widely recommended as the first line treatment in TCAs intoxication but the best method of its administration has not been yet established therefore, we decided to compare the ef...

[ 5 ] - Puzzling situation of acetaminophen toxicity in a referral hospital, Tehran, Iran

Puzzling situation of acetaminophen toxicity in a referral hospital, Tehran, Iran Acetaminophen carries a higher risk of overdose. A puzzling situation of acetaminophen toxicity was encouraging enough to explore the epidemiologic situation of acetaminophen toxicity and its outcomes among patients acquired poisoning. This cross-sectional study retrospectively reviewed the medical r...

[ 6 ] - Acetaminophen Analysis in Different Commercial Formulation of Iranian Acetaminophen Tablets

Acetaminophen is one of the most important antipyretic and analgesic drugs. It has an excellent efficacy when it's used in therapeutic doses, but in unsafe doses it can be resulted in hepatotoxicity and permanent liver failure. Due to disparities that have been reported between the actual and stated concentration of acetaminophen tablets, we aimed to compare the actual quantity of 8 Iranian gen...