In this Policy Review, the Bone Working Group of International Myeloma updates its clinical practice recommendations for management multiple myeloma-related bone disease. After assessing available literature and grading using Grading Recommendations, Assessment, Development, Evaluations (GRADE) method, experts from working group recommend zoledronic acid as preferred bone-targeted agent patient...

thallium 201 whole body scintigraphy was performed in a 30 year old patient with diffuse osseous metastatic disease secondary to glioblastoma multiforme. multiple sites of thallium uptake correlated with the findings on serial bone scans and radiographs. bone biopsy of a lower lumbar vertebra confirmed that the metastases were of glial origin.

albright syndrome is a rare condition, usually appears in the early years of life and characterized by bending or thickening of long bones. in girls, of endocrine glands disorders especially precocious puberty are the most common symptoms. also, brown pigments in the skin are another sing of this syndrome. certain mucosal and skin pigments are considerable features of the disease. etiology and ...

BACKGROUND: Dental disease, trauma and maxillofacial surgeries can cause alveolar bone defects. Among different kinds of treatment, autogenous bone grafts is accepted as a golden standard. On the other hand, because of limitation of treatment with autogenous bone grafts, osteogenic cells derived from stem cells are suggested. OBJECTIVES: The aim of this study was to compare the mean density of ...

BackgroundCongenital generalized lipodystrophy (CGL) is a rare disease. It is associated with near total fat loss, severe insulin resistance and hypoleptinemia leading to metabolic derangements.Case PresentationWe report a 25- year- old female with 1-Acylglycerol-3-phosphate-O-acyltransferase 2 (APGAT2) mutation, and both sclerotic and lytic bone lesions together for the first time. Bone cyst i...