Mechanical stimulus has been identified for a long time as a key player in the adaptation of the musculo-skeletal tissues to their function. Mechanical loading is then an intrinsic variable to be considered when new developments are proposed in bone tissue engineering. By combining structural biomechanics and mechanotransduction aspects, a new paradigm is presented for bone tissue engineering. ...

Bone tissue reconstruction with extensive damage is one of the challenges for dentists because its healing process bone tissue. graft gold standard repair. However, use has a limited amount produced. Tissue engineering latest method in terms regeneration. three main components, first stem cells that have self renewal ability and multineage differentiation, second bioreactor / growth factor, the...

Objective (s): The scarcity of articular cartilage defect to repair due to absence of blood vessels and tissue engineering is one of the promising approaches for cartilage regeneration. The objective of this study was to prepare an extracellular matrix derived decellularized bovine articular cartilage scaffold and investigate its interactions with seeded rat bone marrow mesenchymal stem cells (...

traumatic brain injury (tbi) is a common reason of brain tissue loss as a result of tumors, accidents, and surgeries. renewal of the brain parenchyma is restricted by many reasons such as inimical substances produced as the result of trauma and also inflammatory responses. a strong cascade of inflammatory responses begins as a result of tbi which include recalling peripheral leukocytes into the...

Bone tissue engineering and bone scaffold development represent two challenging fields in orthopaedic research. Micro-computed tomography (mCT) allows non-invasive measurement of these scaffolds' properties in vivo. However, the lack of standardized mCT analysis protocols and, therefore, the protocols' user-dependency make interpretation of the reported results difficult. To overcome these issu...