نتایج جستجو برای: bsmi polymorphism and vitamin d receptor gene
تعداد نتایج: 17155683 فیلتر نتایج به سال:
Background & Aims: Tuberculosis is the second factor in the deaths caused by infectious diseases in the world. Out of every ten infected people, only in one the clinical symptoms of the disease is developed. The correct vitamin D receptor activity on the nuclei of macrophages is one of the main components of the host innate immunity against M. tuberculosis. In the present study, the relation...
Background: Lots of vitamin D functions are mediated by its steroid family receptor (VDR). Vitamin D role in infertility is reported by significant fertility reduction in many male laboratory animals with vitamin D deficiency. The reason for reduced fertility in male VDR-null mouse model has been reported to be reduced sperm count and sperm motility. Vitamin D has effects on sperm motility, spe...
The hormonally active form of vitamin D3, 1,25(OH)2D3 (calcitriol), exerts actions through VDR receptor, which acts as a transcriptional factor. Calcitriol is an immunomodulator that affects various immune cells, and several studies link it to many autoimmune diseases. BsmI polymorphism affects the level of VDR gene transcription, transcript stability, and posttranscriptional modifications. It ...
The prevalence of vitamin D deficiency, presenting as hypocalcemic seizures or rickets in children, is increasing worldwide due to insufficient vitamin D intake and lack of exposure to sunshine. However, considering that relatively few children with low 25-hydroxyvitamin D [25(OH)D] levels manifest symptoms, it is possible that genetic factors may predispose individuals to vitamin D deficiency...
BACKGROUND AND OBJECTIVES Vitamin D and folate are highly UV sensitive, and critical for maintaining health throughout the lifecycle. This study examines whether solar irradiance during the first trimester of pregnancy influences vitamin D receptor (VDR) and nuclear folate gene variant occurrence, and whether affected genes influence late-life biochemical/clinical phenotypes. METHODOLOGY 228 ...
Lead is a ubiquitous environmental pollutant that poses serious health problems to humans, especially children. However, genetic variability in individuals varies their susceptibility lead poisoning. One possible factor polymorphism. Thus, this study aimed investigate the association between blood level (BLL), and polymorphisms delta-aminolevulinic acid dehydratase (ALAD) MspI (rs1800435) vitam...
BACKGROUND Our objective was to conduct a systematic review and meta-analysis of prospective studies on colorectal cancer (CRC) and vitamin D intake and 25-hydroxyvitamin D status, as part of the World Cancer Research Fund Continuous Update Project. We also aimed at conducting meta-analysis of all studies on CRC and vitamin D receptor (VDR) single-nucleotide polymorphisms. METHODS Relevant st...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید