The lectin pathway of complement is considered to be the most ancient complement pathway as inferred from identification of ancient homologs of mannose-binding lectin (MBL) and MBL-associated serine proteases (MASPs) in some invertebrates. MBL homologs with galactose selectivity and an MASP3-like sequence also occur in bony fish, linking the evolution of the lectin complement pathway from inver...

DoD operates many system high enclaves with limited information ow between enclaves at diierent security levels. Too often, the result is duplication of operations and inconsistent and untimely data at different sites, which reduces the eeectiveness of DoD decision support systems. This paper describes our solution to this problem as it arises in installations of the Joint Maritime Command Info...

SISO Military Scenario Definition Language (MSDL) and Coalition Battle Management Language (C-BML) continue to progress as a means to interoperate Command and Control (C2) systems with simulation systems. However, the ability to use these powerful interoperation technologies is limited to national military groups who possess a C2 or simulation system and choose to invest in an MSDL/C-BML interf...

The Department of Defense has focused much attention in recent years to the use of modeling and simulation for developing and analyzing the military systems of the future. Decreasing budgets, coupled with the necessity of being prepared for multi-faceted types of military activities, such as humanitarian interventions, joint peacekeeping efforts, and other “Missions-other-thanWar” have created ...

The Navy Program Executive Office (C4I and Space) PMW-170 has been at the forefront of new efforts to improve UHF SATCOM bandwidth utilization of existing satellite communications assets. This effort is synchronized with the Navy’s transition of legacy information exchange (IXS) circuits to modern IP network based applications. The Assured IP (AIP) project, started by PMW-179 and now managed by...

MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of other genes by transcriptional inhibition or translational repression. miR-34a is a known tumor suppressor gene and inhibits abnormal cell growth. However, its role in other tumorigenic processes is not fully known. This study aimed to investigate the action of miR-34a on cell invasion. We found that miR-34a is express...

Two hundred and ten patients with meningismus and the infections of the central nervous system (CNS) with the clinical symptoms and signs of the acute serous meningitis syndrome, were divided in to groups according to etiology (enterovirus meningitis-ENTERO, serous meningitis various etiology-SM and tuberculous meningitis-TBC). Intrathecal synthesis (ITS) of C3c and C4 complement components and...

The fourth component of human complement (C4) in 102 individual plasma samples has been examined by the technique of antigen-antibody crossed electrophoresis (AACE). Electrophoretic heterogeneity of C4 was manifested by the repeated occurrence of seven different precipitin patterns. These patterns were formed by varying combinations of three subtypes of C4, differing in electrophoretic mobility...