Cap-analysis gene expression (CAGE) Basic and Analysis Databases store an original resource produced by CAGE, which measures expression levels of transcription starting sites by sequencing large amounts of transcript 5' ends, termed CAGE tags. Millions of human and mouse high-quality CAGE tags derived from different conditions in >20 tissues consisting of >250 RNA samples are essential for iden...

MicroRNA array analysis revealed that miR-217 expression was decreased in anti-cancer drug-resistant Malme3MR cancer cells. CAGE, a cancer/testis antigen, was predicted as a target of miR-217. Luciferase activity and ChIP assays revealed a negative feedback relationship between CAGE and miR-217. miR-217 and CAGE oppositely regulated the response to anti-cancer drugs such as taxol, gefitinib and...

There are relatively few experimental studies and risk assessments of the effects on non-target insects from ultra-low volume (ULV) insecticides used for management of adult mosquitoes. Therefore, we evaluated factors that may influence the ability of an insect to intercept the insecticide at the time of application by using Hippodamia convergens (Coleoptera: Coccinellidae) in field bioassay ex...

The results from an experimental and numerical study of a known mouse cage (static microisolator type) placed in a wind tunnel are presented. The study involved the collection of experimental airflow data and the use of these data in the validation of the computational fluid dynamics (CFD) cage model. This validation was important as it then allowed the CFD cage model to be used to represent ca...

Behaviour and use of the cage area were studied in 96 rabbits (Oryctolagus cuniculus) kept in an enriched cage system - with access to shelter and raised height at the back of the cage - and in a conventional cage system to estimate the effects of the environmental enrichment on the rabbits' welfare. The rabbits' behaviour and placement in the cage were observed, using continuous video recordin...

An operational definition of collective cage variables previously introduced for liquid argon is extended, via a molecular dynamics study, to the rotational properties of axially symmetric molecules. Quantitative measures of the static and dynamic cage properties are extracted for liquid Cl2 near the triple point. The collective cage variables are well described by the potential acting on an ar...